Hi Daniel,
I agree, those flip angle differences are quite big and would make a
difference to contrast. I suspect gray/white contrast is better for the
higher TI and lower flip angles in those scans (and they could benefit
from longer TR). So if you have a balanced study/control group it's ok
Dear all,
We are designing a study based on clinical data. We want to work with a
MPRAGE sequence but subjects have been given 4 different sets of parameters:
- TR: 1900; TE: 4,38; TI: 1100; flip angle: 15
- TR: 1900; TE: 3,55; TI: 1100; flip angle: 15
- TR: 1900; TE: 3,39; TI: 900; flip angle:
Hi Daniel
those are pretty big differences in flip angle. I'll cc Andre van der Kouwe
on this so he can comment, but I would be hesitant. The increased TE will
have a big effect on dura (darkening it), but will also reduce gray/white
contrast.
cheers
Bruce
On Fri, 17 Aug 2012, Daniel
