Re: [Freesurfer] are there any previous studies on the robustness of freesurfer default parameters as used in cortical thickness computation?

Hi Mark that's a tough question to answer, as it depends on the parameter. I'm sure that the answer is yes for some, but in general we try very hard to adaptively estimate our parameters, which is why our tools work well on a wide variety of T1-weighted acquisitions. We also have a test suite

Re: [Freesurfer] are there any previous studies on the robustness of freesurfer default parameters as used in cortical thickness computation?

Hi Bruce, Yes - of course that helps :) I did not even know that it was a hard question! I had noticed that some results from freesurfer, and other segmentation techniques, subsequently fail manual QC. Do you think that there would be value in some kind of parameter sensitivity

[Freesurfer] are there any previous studies on the robustness of freesurfer default parameters as used in cortical thickness computation?

Hi, My interest is in cortical thickness measurements for longitudinal Alzheimer data, namely the ADNI dataset. My understanding is that recon-all can be used to generate cortical thicknesses. I am trying to understand how the default parameter values used in recon-all were arrived at. Are