Re: [Freesurfer] significant of long_mris_slopes

[Martin Reuter]

Hi Lanbo, 


the first command computes the slope of within-subject linear fits (the rate, 
so the unit is mm/time). You use —generic time which means that the time is 1 2 
3 … It is better to put the real time, e.g. in years for a longitudinal study. 

the second command is a one-sample-group-mean (OSGM) analysis to test whether 
the slopes are significantly different from zero. The sig.table.dat shows the 
significances (log 10 , so 1 is p=0.1, 2 is p=0.01 etc, with a sign showing the 
direction). 

Now if you look at regular aging and if you have enough subjects and wait for a 
year or two all regions in the brain should show significant atrophy. So the 
OSGM is not very interesting usually. For a real study you usually need two 
groups (diseased vs control, or drug vs no-drug)

Best, Martin


> On 27. Oct 2017, at 20:13, lanbo Wang  wrote:
> 
> Dear freesurfer group,
> 
> Hi!
> I used long_stats_slopes and code to process my longitudinal data:
> long_stats_slopes --qdec sub_qdec_long.dat --stats lh.aparc.stats --meas 
> thickness --sd $SUBJECTS_DIR --do-rate --generic-time --stack-rate 
> thickness.lh.aparc-rate.stack.txt
> mri_glmfit --osgm --glmdir thickness.lh.aparc-rate --table 
> thickness.lh.aparc-rate.stack.txt
> I got results sig.table.dat in folder of 'thickness.lh.aparc-rate'. I want to 
> ask what's meaning of this results. Is it the significant results or just 
> directly result?
> 
> All best,
> Lanbo Wang 
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> Freesurfer mailing list
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[Freesurfer] significant of long_mris_slopes

[lanbo Wang]

Dear freesurfer group,

Hi!
I used long_stats_slopes and code to process my longitudinal data:
long_stats_slopes --qdec sub_qdec_long.dat --stats lh.aparc.stats --meas
thickness --sd $SUBJECTS_DIR --do-rate --generic-time --stack-rate
thickness.lh.aparc-rate.stack.txt
mri_glmfit --osgm --glmdir thickness.lh.aparc-rate --table
thickness.lh.aparc-rate.stack.txt
I got results sig.table.dat in folder of 'thickness.lh.aparc-rate'. I want
to ask what's meaning of this results. Is it the significant results or
just directly result?

All best,
Lanbo Wang


sig.table.dat
Description: Binary data
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