just wondering if anyone else in Galaxy land was having this problem, I emailed tophat.cufflinks@ to let them know
We have been experiencing segmentation faults with cufflinks 1.0.3. Our platform is CentOS 5.5, and we compiled from source using gcc 4.1.2 (Red Hat 4.1.2-48). The segmentation fault occured when we passed in a GTF annotation file with the -G option. Using gdb, I tracked it down to line 218 in bundles.cpp: string rs = (rna_seq) ? rna_seq:""; It appeared that in our case rna_seq was uninitialized and did not point to a valid C string. char* rna_seq; if (loadSeqs && faseq) { rna_seq = rna.getSpliced(faseq, false, &seqlen); } ... if (loadSeqs) { string rs = (rna_seq) ? rna_seq:""; ... } As you can see, it would be possible for the first if-block to not execute, but the second one to still execute (loadSeqs = true, faseq = false). I tried making the following change to the declaration of rna_seq to initialize it to NULL: char* rna_seq = 0; this stopped the segmentation fault we were seeing -- Glen L. Beane Senior Software Engineer The Jackson Laboratory (207) 288-6153 ___________________________________________________________ Please keep all replies on the list by using "reply all" in your mail client. To manage your subscriptions to this and other Galaxy lists, please use the interface at: http://lists.bx.psu.edu/