dwgsim (and dwgsimeval) may be useful to you:

http://toolshed.g2.bx.psu.edu/view/nilshomer/dwgsim
http://toolshed.g2.bx.psu.edu/view/nilshomer/dwgsim_eval

Good luck,
J.


On Jun 24, 2013, at 11:47 PM, מירב . wrote:

> Hi,
> 
> I want to do some checks on tools I'm using(in this case I'm checking 
> svdetect).
> I have a program that creats .fasta file of genome with some structural 
> variants.
> Now I need a tool wich will simulate the  illumina's sequencing read and 
> output .fastq files(or .sam files).
> Does galaxy have such tool?
> If not, do you have suggestion for something out of galaxy?
> 
> Thanks for your help
> 
> merav
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