Re: [galaxy-user] SNPEff - Reports Gain of Stop Codon as FRAME_SHIFT in some cases

Thanks John, Pablo, Updates are of course welcomed in the Tool Shed. Thanks for letting the Galaxy community aware that this may come up during analysis. Best, Jen Galaxy team On 12/13/11 12:17 PM, John David Osborne wrote: Hi Pablo, Correct me if I am wrong, but I believe that SNPEff

[galaxy-user] SNPEff - Reports Gain of Stop Codon as FRAME_SHIFT in some cases

Hi Pablo, Correct me if I am wrong, but I believe that SNPEff doesn't check the inserted sequence when computing the effect of an insertion? For instance an insertion of TTTA will be reported as a frameshift mutation. In the majority of cases this is fine, however if the current reading frame