I think the issue, as I read it, is that Will’s data is only NIFTI currently, 
so he doesn’t have any subject CIFTI that he could use for the stage 1 of dual 
reg.

Our suggestion of course to remedy that would be that you process your data 
into CIFTI, using the HCP Pipelines. ☺

Cheers,
-MH

--
Michael Harms, Ph.D.
-----------------------------------------------------------
Associate Professor of Psychiatry
Washington University School of Medicine
Department of Psychiatry, Box 8134
660 South Euclid Ave.                        Tel: 314-747-6173
St. Louis, MO  63110                          Email: mha...@wustl.edu

From: <hcp-users-boun...@humanconnectome.org> on behalf of Stephen Smith 
<st...@fmrib.ox.ac.uk>
Date: Tuesday, March 13, 2018 at 2:31 AM
To: Will Khan <khan.wa...@florey.edu.au>
Cc: "hcp-users@humanconnectome.org" <hcp-users@humanconnectome.org>
Subject: Re: [HCP-Users] Melodic ICA idle

Hi Will

I'm not aware of any outstanding bugs in melodic that would cause it to 
silently hang.  Are you sure it's not just that you've run out of RAM and are 
swapping?

Yes it's better to do group-ICA on grayordinates. You can still dual-regress 
that (step one into subject CIFTI, step two back into either CIFIT and/or 
volume) to get volume maps back, like we did for the most recent group-ICA HCP 
release.

Cheers.





On 13 Mar 2018, at 04:52, Will Khan 
<khan.wa...@florey.edu.au<mailto:khan.wa...@florey.edu.au>> wrote:

Dear HCP Users,

I am currently using the ICA-FIX denoised volumetric data for 100 unrelated 
subjects. I come across an issue where melodic appears to 'choke' or remain 
idle for a considerable amount of time at the variance normalisation step. I am 
running a group-ICA within a mask of the PCC.

I understand this issue has been reported by others and appears to be a bug 
with the melodic command.

I know Steve Smith and others have cautioned against the use of the volumetric 
data - but I am using the HCP dataset to generate group-ICA maps that I later 
wish to dualreg onto a patient dataset. Since all my patient data is in NIFTI 
format I am initially hesitant to use CIFTI (please correct me if I am wrong 
here).

Am I right to be using the volumetric data in this case?

Many Thanks!

Regards,

Will





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