Angel,
Thank you for your suggestions. I will look into them and see if it works
for me.
But, ideally I would like a script that can be used to mutate any given
residue on-the-fly in response to a command such as:
> mutate LYS63 ALA
Amjad
On Thu, Aug 8, 2013 at 1:36 PM, Angel Herráez wrote:
Hi Amjad
I've heard that question several times and I always reply "it cannot be done
in Jmol, you need a modelling software".
This is really tricky. I mean, the result is hardly reliable. But I see your
point.
I haven't seen what PDBViewer does for that.
I would say this is a reasonable way t
Hi Jeff,
Thanks for your response.
I fully agree--ideally one needs an NMR or x-ray structure to compare
structural changes in wildtype versus mutant protein.
However, it is sometimes useful to mutate a residue on-the-fly to
demonstrate to novices how such a mutation might create a lethal cavity
Compare how? Do you want to see how the mutation affects the structure?
Really need and X-ray or NMR structure of each for that to have any real
meaning.
***
Jeff Hansen, Professor and Chair
Department of Chemistry and Biochemistry
DePauw University
Hi guys,
Is it possible to mutate an amino acid in JMol.
For example, how can I introduce the K63A mutation (mutate lysine 63 to
alanine) into my protein to compare wildtype versus mutant?
What is the JMol command?
Thanks!
Amjad
--
Hi guys,
Is it possible to mutate an amino acid in JMol. For example, how can I
introduce the K63A mutation (mutate lysine 63 to alanine) into my protein
to compare wildtype versus mutant? What is the JMol command?
Amjad
--
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