Dear colleagues,

We are pleased to announce the recent publication of the following article
in Aquatic Mammals: The Evaluation of Olfaction in Stranded California Sea
Lions (*Zalophus californianus*) and Its Relevance to Domoic Acid Toxicosis

Lauren M. De Maio, Peter F. Cook, Colleen Reichmuth, and Frances M. D.
Gulland. 2018. The Evaluation of Olfaction in Stranded California Sea Lions
(*Zalophus californianus*) and Its Relevance to Domoic Acid Toxicosis.
Aquatic Mammals, 44(3), 231-238. DOI: https://doi.org/
10.1578/AM.44.3.2018.231

Abstract: Domoic acid is an algal toxin that has caused neurologic disease
and reproductive failure in California sea lions (*Zalophus californianus*).
In affected sea lions, necrotic neurons have been observed in the olfactory
bulb and pyriform lobe of the brain, indicating potential for disrupted
olfactory capability in addition to other documented neurological effects.
Sea lions use olfaction in social interactions, and deficits could lead to
maladaptive interactions, including between mothers and pups. Here, to
assess olfactory capability in wild California sea lions, we developed a
behavioral assay for use in a clinical context. We tested 24 stranded sea
lions with no apparent neurological symptoms, and 22 sea lions with a
clinical diagnosis of chronic domoic acid toxicosis, probing differential
responses to a scented and non-scented object. The neurologically healthy
animals spent significantly more time with the scented object than with the
non-scented object, establishing this method as effective in demonstrating
olfactory discrimination in California sea lions. The domoic acid toxicosis
group showed a non-significant reduction in response to the scented stimulus.
However, the variability suggests that olfactory sensitivity is impaired in
at least some sea lions with domoic acid toxicosis.



Please do not hesitate to contact me for a copy of the publication at
lauren.dem...@noaa.gov.

Best wishes,

Lauren De Maio
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