Re: [NMusers] OMEGA off-diagonal elements parameterized as correlations

2009-07-11 Thread Nick Holford
[mailto:owner- nmus...@globomaxnm.com] On Behalf Of Nick Holford Sent: Saturday, 11 July 2009 6:31 a.m. To: nmusers Subject: Re: [NMusers] OMEGA off-diagonal elements parameterized as correlations Alison, Thanks very much for taking the time to document the history of the CORRELATION option. I hope

Re: [NMusers] OMEGA off-diagonal elements parameterized as correlations

2009-07-10 Thread Alison Boeckmann
Nick, I can only offer you a litle bit of history. The CORRELATION option for $OMEGA was supported by NMTRAN and described in NONMEM VI's help guide during most of its development, from Oct 2000 till at least May 2005. Several other interesting new options were described, such as VARIANCE vs.

Re: [NMusers] OMEGA off-diagonal elements parameterized as correlations

2009-07-08 Thread saik.urien.svp
To: nmusers@globomaxnm.com Sent: Wednesday, July 08, 2009 2:36 PM Subject: [NMusers] OMEGA off-diagonal elements parameterized as correlations Dear all, I was wondering if it is possible to insert the off-diagonal elements of OMEGA as correlations rather than covariances, because I find it more