Hybrid Genetic Algorithm Approaches to Model Selection

Speaker: Robert Bies, Pharm.D. Ph.D
 Associate Professor of Pharmaceutical Sciences,
Member Computational and Data Enabled Sciences Program
University at Buffalo, NY

Thursday, Oct 24, 2019, 12:00 to 1:00 pm EDT

Register for free at https://www.rosaandco.com/webinars

Abstract:
A newly implemented version of an established Genetic Algorithm based approach 
using NONMEM with some modifications into an R-shiny package that provides the 
same functionality with additional flexibility is presented.

Some refinements have been made in the selection process for evaluating models 
compared with the original evolutionary algorithm. Several population analyses 
using the updated algorithm are compared with results obtained using classical 
stepwise approaches in xenograft tumor growth profiles and population 
pharmacokinetic analyses

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