RE: [NMusers] $Error log transformed

2016-12-16 Thread Andrzej Bienczak
Hi, This problem was discussed before on NMUSERS, here's a link with code suggested by Leonid Gibiansky and Mats Karlsson (code allowing for a combined - additive and proportional error in log space): http://www.cognigencorp.com/nonmem/nm/98may202004.html You model the log transformed

RE: [NMusers] $Error log transformed

2016-12-16 Thread R.terHeine
Hi Katrin, You'll have to take the natural logarithm of your DVs I would change your error block to: $ERROR IPRED=LOG(F+1E-16) ; Protection against LOG(0) in case of dosing events etc Y=IPRED+ERR(1) ; FOR PROPORTIAL ERROR Cheers! Rob Van: owner-nmus...@globomaxnm.com