[NMusers] Environment variable LIBRARY_PATH

2007-03-19 Thread Martin Fransson
Hello, Can anyone please tell me exactly what is the purpose of setting the environment variable LIBRARY_PATH=c:\g77\lib for G77 in Windows XP? This setting will create a conflict with another program I have installed. The conflict is possibly related to the use of mingw. However, if I delete

Re: [NMusers] General question on modeling

2007-03-19 Thread AJ Rossini
I'd highly recommend reading Frank Harrell's book on Regression Modeling if you think that stepwise regression makes any sense. While much of the book applies to linear and generalized linear (i.e. categorical, etc) regression models, nonlinear models (and mixed effects models) would

Re: [NMusers] General question on modeling

2007-03-19 Thread Nick Holford
Mark, If we are talking about science then we are not talking about regulatory decision making. The criteria used for regulatory approval and labelling are based on pragmatism not science e.g. using intention to treat analysis (use effectiveness rather than method effectiveness), dividing a

RE: [NMusers] General question on modeling

2007-03-19 Thread Stephen Duffull
Mark hence engineering). Reality is that the vast majority of providers couldn't deal with renal function as a continuous variable in dosing. I very much hope that this is a misinformed perception by industry rather than a reality. Presumably weight is considered continuous and in