Re: [NMusers] What would the impact be, if NONMEM runs 10 times faster than now?

2008-09-12 Thread Michael . J . Fossler
You mean, besides getting to go home earlier? ;^)) BAE, KYUN-SEOP [EMAIL PROTECTED] Sent by: [EMAIL PROTECTED] 12-Sep-2008 12:40 To nmusers@globomaxnm.com cc Subject [NMusers] What would the impact be, if NONMEM runs 10 times faster than now? Dear NMusers, I would like to ask the

[NMusers] modeling binary observations

2008-09-12 Thread Zhang, Yi [CNTUS]
Dear All : I'd like to get your opinion on this: when modeling an event (0/1) that is caused by an cumulative effect, 1. would cumulative AUC be a better predictor than concentration, since CAUC can better capture the accumulative process? 2. If CAUC is used, is there good ways to

RE: [NMusers] What would the impact be, if NONMEM runs 10 times faster than now?

2008-09-12 Thread Mark Sale - Next Level Solutions
Kyun-Seopsee:http://www.ecpag.org/presentations/2006/0725/5_MarkSale.pdfMarkMark Sale MD Next Level Solutions, LLC www.NextLevelSolns.com 919-846-9185 Original Message Subject: [NMusers] What would the impact be, if NONMEM runs 10 times faster than now? From: "BAE, KYUN-SEOP"

Re: [NMusers] modeling binary observations

2008-09-12 Thread Nick Holford
Yi, Without you giving us any further details of the process you are describing I can only offer some general idea of how you might approach this. Given that you think that a binary outcome is dependent on the cumulation of something I am assuming the cumulation is with respect to time.