]
Sent: 21 August 2009 13:57
To: Ribbing, Jakob; Pyry Välitalo; nmusers@globomaxnm.com
Subject: RE: [NMusers] Calculating shrinkage when some etas are zero
Hi Pyry and Jacob,
If you exclude zero etas then what happens to infomative individuals who
just happen to have the population typical values
] Calculating shrinkage when some etas are zero
Hi to all,
Do you know if there is a quick method to exclude subjects with ETA=0 from the
calculation of ETA shrinkage using NONMEM 7?
I also tried to use the option –shrinkage of PsN, but I get the following
error:
AN ERROR WAS FOUND IN THE CONTROL
Välitalo
pyry.valit...@gmail.com, nmusers@globomaxnm.com
Subject
Re: [NMusers] Calculating shrinkage when some etas are zero
Hello Jakob, et al.
I would agree that individuals who do not contribute data to the
estimation of a particular element of OMEGA should be excluded from
; Ribbing, Jakob; nmusers@globomaxnm.com;
owner-nmus...@globomaxnm.com; Pyry Välitalo
*Subject:* Re: [NMusers] Calculating shrinkage when some etas are zero
Hi to all,
Do you know if there is a quick method to exclude subjects with ETA=0
from the calculation of ETA shrinkage using NONMEM 7?
I also tried
...@anest.umcg.nl,
'Ribbing, Jakob' jakob.ribb...@pfizer.com, nmusers@globomaxnm.com,
'Pyry Välitalo' pyry.valit...@gmail.com
Subject
Re: [NMusers] Calculating shrinkage when some etas are zero
(this message is also resent, sorry if it is doubled)
Hello Marco,
To filter out ETA=0 with PsN you need
Hi all,
I saw this snippet of information on PsN-general mailing list.
Kajsa Harling wrote in PsN-general:
I talked to the experts here about shrinkage. Apparently, sometimes an
individual's eta may be exactly 0 (no effect, placebo, you probably
understand this better than I do). These zeros
@globomaxnm.com
Subject: [NMusers] Calculating shrinkage when some etas are zero
Hi all,
I saw this snippet of information on PsN-general mailing list.
Kajsa Harling wrote in PsN-general:
I talked to the experts here about shrinkage. Apparently, sometimes an
individual's eta may be exactly 0 (no effect
...@globomaxnm.com namens Ribbing, Jakob
Verzonden: vr 21-8-2009 12:26
Aan: Pyry Välitalo; nmusers@globomaxnm.com
Onderwerp: RE: [NMusers] Calculating shrinkage when some etas are zero
Hi Pyry,
Yes, when calculating shrinkage or looking at eta-diagnostic plots it is often
better to exclude etas
would more trust diagnostics after
exclusion.
Jakob
From: Eleveld, DJ [mailto:d.j.elev...@anest.umcg.nl]
Sent: 21 August 2009 13:57
To: Ribbing, Jakob; Pyry Välitalo; nmusers@globomaxnm.com
Subject: RE: [NMusers] Calculating shrinkage when some etas are zero
[mailto:d.j.elev...@anest.umcg.nl]
Sent: 21 August 2009 13:57
To: Ribbing, Jakob; Pyry Välitalo; nmusers@globomaxnm.com
Subject: RE: [NMusers] Calculating shrinkage when some etas are zero
Hi Pyry and Jacob,
If you exclude zero etas then what happens to infomative individuals
who just happen
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