Re: [NMusers] Calculating shrinkage when some etas are zero

2010-12-07 Thread marco . campioni
] Sent: 21 August 2009 13:57 To: Ribbing, Jakob; Pyry Välitalo; nmusers@globomaxnm.com Subject: RE: [NMusers] Calculating shrinkage when some etas are zero Hi Pyry and Jacob, If you exclude zero etas then what happens to infomative individuals who just happen to have the population typical values

RE: [NMusers] Calculating shrinkage when some etas are zero

2010-12-07 Thread Andrew Hooker
] Calculating shrinkage when some etas are zero Hi to all, Do you know if there is a quick method to exclude subjects with ETA=0 from the calculation of ETA shrinkage using NONMEM 7? I also tried to use the option –shrinkage of PsN, but I get the following error: AN ERROR WAS FOUND IN THE CONTROL

Re: [NMusers] Calculating shrinkage when some etas are zero

2010-12-07 Thread Kajsa Harling
Välitalo pyry.valit...@gmail.com, nmusers@globomaxnm.com Subject Re: [NMusers] Calculating shrinkage when some etas are zero Hello Jakob, et al. I would agree that individuals who do not contribute data to the estimation of a particular element of OMEGA should be excluded from

Re: [NMusers] Calculating shrinkage when some etas are zero

2010-12-07 Thread Kajsa Harling
; Ribbing, Jakob; nmusers@globomaxnm.com; owner-nmus...@globomaxnm.com; Pyry Välitalo *Subject:* Re: [NMusers] Calculating shrinkage when some etas are zero Hi to all, Do you know if there is a quick method to exclude subjects with ETA=0 from the calculation of ETA shrinkage using NONMEM 7? I also tried

Re: [NMusers] Calculating shrinkage when some etas are zero

2010-12-07 Thread marco . campioni
...@anest.umcg.nl, 'Ribbing, Jakob' jakob.ribb...@pfizer.com, nmusers@globomaxnm.com, 'Pyry Välitalo' pyry.valit...@gmail.com Subject Re: [NMusers] Calculating shrinkage when some etas are zero (this message is also resent, sorry if it is doubled) Hello Marco, To filter out ETA=0 with PsN you need

[NMusers] Calculating shrinkage when some etas are zero

2009-08-21 Thread Pyry Välitalo
Hi all, I saw this snippet of information on PsN-general mailing list. Kajsa Harling wrote in PsN-general: I talked to the experts here about shrinkage. Apparently, sometimes an individual's eta may be exactly 0 (no effect, placebo, you probably understand this better than I do). These zeros

RE: [NMusers] Calculating shrinkage when some etas are zero

2009-08-21 Thread Ribbing, Jakob
@globomaxnm.com Subject: [NMusers] Calculating shrinkage when some etas are zero Hi all, I saw this snippet of information on PsN-general mailing list. Kajsa Harling wrote in PsN-general: I talked to the experts here about shrinkage. Apparently, sometimes an individual's eta may be exactly 0 (no effect

RE: [NMusers] Calculating shrinkage when some etas are zero

2009-08-21 Thread Eleveld, DJ
...@globomaxnm.com namens Ribbing, Jakob Verzonden: vr 21-8-2009 12:26 Aan: Pyry Välitalo; nmusers@globomaxnm.com Onderwerp: RE: [NMusers] Calculating shrinkage when some etas are zero Hi Pyry, Yes, when calculating shrinkage or looking at eta-diagnostic plots it is often better to exclude etas

RE: [NMusers] Calculating shrinkage when some etas are zero

2009-08-21 Thread Ribbing, Jakob
would more trust diagnostics after exclusion. Jakob From: Eleveld, DJ [mailto:d.j.elev...@anest.umcg.nl] Sent: 21 August 2009 13:57 To: Ribbing, Jakob; Pyry Välitalo; nmusers@globomaxnm.com Subject: RE: [NMusers] Calculating shrinkage when some etas are zero

Re: [NMusers] Calculating shrinkage when some etas are zero

2009-08-21 Thread Gastonguay, Marc
[mailto:d.j.elev...@anest.umcg.nl] Sent: 21 August 2009 13:57 To: Ribbing, Jakob; Pyry Välitalo; nmusers@globomaxnm.com Subject: RE: [NMusers] Calculating shrinkage when some etas are zero Hi Pyry and Jacob, If you exclude zero etas then what happens to infomative individuals who just happen