[NMusers] Calculating shrinkage when some etas are zero

Hi all, I saw this snippet of information on PsN-general mailing list. Kajsa Harling wrote in PsN-general: I talked to the experts here about shrinkage. Apparently, sometimes an individual's eta may be exactly 0 (no effect, placebo, you probably understand this better than I do). These zeros

[NMusers] IOV with Mu modeling, using EM algorithms

to hear your thoughts! Best wishes, Pyry Välitalo Postdoc, Leiden University, Division of Pharmacology Senior Scientist, Orion Pharma, Drug Disposition and Pharmacometrics

Re: [NMusers] Observed (yaxis) vs Predicted (xaxis) Diagnostic Plot - Scientific basis.

re mine alone, and not necessarily those of my employer. Best wishes, Pyry Välitalo PK Assessor at Finnish Medicines Agency On Fri, 18 Aug 2023 at 10:59, Martin Bergstrand < martin.bergstr...@pharmetheus.com> wrote: > Dear Joga and all, > > Joga makes a valuable point that all