RE: [External email][NMusers] Sad news about Dr. Ludden

[Stephen Duffull]

I agree.  While I only met Tom in person a few times we interacted quite a bit 
in my early days of PMx and NONMEM.  Tom was immensely clever, kind, 
unassuming, understanding and supportive.  A pleasure to chat with and to learn 
from.



Steve

Stephen Duffull
Senior Scientific Advisor, Certara Drug Development Solutions
stephen.duff...@certara.com<mailto:stephen.duff...@certara.com>
Dunedin, Aotearoa New Zealand (NZ Time Zone: UTC +12)
www.certara.com<http://www.certara.com/>
[cid:image001.png@01DAE716.8D12FEA0]




From: owner-nmus...@globomaxnm.com  On Behalf Of 
Paul Hutson
Sent: Sunday, August 4, 2024 3:32 AM
To: Ekaterina Gibiansky ; Diane Mould 
; Riley, Steve ; 
nmusers@globomaxnm.com
Subject: RE: [External email][NMusers] Sad news about Dr. Ludden

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What a giant.  I always appreciated his kindness in responding to my naiive 
questions about coding NONMEM.

Paul R. Hutson, PharmD, BCOP
Professor (CHS)
UW School of Pharmacy
Director, UW Madison Transdisciplinary Center for Research in Psychoactive 
Substances<https://www.research.pharmacy.wisc.edu/tcrps>
Faculty Leader, Paul P. Carbone Comprehensive Cancer Center Cancer Pharmacology 
Laboratory<https://cancer.wisc.edu/research/resources/ddc/cancer-pharmacology/>
T: 608.263.2496
paul.hut...@wisc.edu<mailto:paul.hut...@wisc.edu>

From: owner-nmus...@globomaxnm.com<mailto:owner-nmus...@globomaxnm.com> 
mailto:owner-nmus...@globomaxnm.com>> On Behalf 
Of Ekaterina Gibiansky
Sent: Friday, August 2, 2024 3:19 PM
To: Diane Mould mailto:drmo...@pri-home.net>>; Riley, 
Steve mailto:steve.ri...@pfizer.com>>; 
nmusers@globomaxnm.com<mailto:nmusers@globomaxnm.com>
Subject: Re: [External email][NMusers] Sad news about Dr. Ludden


I second everything Steve, and Mark, and Diane said. All of us who were blessed 
to work alongside him will forever remember him with fondness and gratitude. 
And let's not forget that he was the only one who Stuart Beal trusted to take 
care of NONMEM and bring it forward into 21st century.

Katya
On 8/2/2024 3:55 PM, Diane Mould wrote:
Dear All
I am very saddened to hear this news.  Tom Ludden was one of the nicest and 
smartest people that I have ever known.  He was a gentle giant in our field and 
I will miss him.
Best
Diane

From: owner-nmus...@globomaxnm.com<mailto:owner-nmus...@globomaxnm.com> 
<mailto:owner-nmus...@globomaxnm.com> On Behalf 
Of Riley, Steve
Sent: Friday, August 2, 2024 2:41 PM
To: nmusers@globomaxnm.com<mailto:nmusers@globomaxnm.com>
Subject: [External email][NMusers] Sad news about Dr. Ludden


CAUTION: This email originated from outside the organization. Do not click 
links or open attachments unless you recognize the sender and know the content 
is safe.
Dear NM-Users,

Regrettably, I am writing to let you know that Dr. Ludden passed away Tuesday 
evening, 30JUL2024.

I was able to get there over the weekend prior to visit him and his family.
During his wakeful moments we had some good scientific discussions.
We talked a lot about NONMEM and how its functionality and utility has expanded 
since he retired. He was pleased to hear about the changes.

He was surrounded by family for the days leading up to the end. They were all 
appreciative that I was able to get there and tell him (and them) how much he 
meant to all of us and the impact he had on our careers.

I think memories of Dr. Ludden were characterized perfectly by Marc Gastonguay, 
"I am forever grateful for the positive impact that Tom had on my life and 
career, not to mention the tremendous, although often underappreciated, 
contributions he made to the disciplines of clinical pharmacology and 
pharmacometrics. His humble brilliance will be missed and fondly remembered."

Steve Riley




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or entity other than the intended recipient is prohibited.

RE: [External email][NMusers] Sad news about Dr. Ludden

[Paul Hutson]

What a giant.  I always appreciated his kindness in responding to my naiive 
questions about coding NONMEM.

Paul R. Hutson, PharmD, BCOP
Professor (CHS)
UW School of Pharmacy
Director, UW Madison Transdisciplinary Center for Research in Psychoactive 
Substances<https://www.research.pharmacy.wisc.edu/tcrps>
Faculty Leader, Paul P. Carbone Comprehensive Cancer Center Cancer Pharmacology 
Laboratory<https://cancer.wisc.edu/research/resources/ddc/cancer-pharmacology/>
T: 608.263.2496
paul.hut...@wisc.edu

From: owner-nmus...@globomaxnm.com  On Behalf Of 
Ekaterina Gibiansky
Sent: Friday, August 2, 2024 3:19 PM
To: Diane Mould ; Riley, Steve ; 
nmusers@globomaxnm.com
Subject: Re: [External email][NMusers] Sad news about Dr. Ludden


I second everything Steve, and Mark, and Diane said. All of us who were blessed 
to work alongside him will forever remember him with fondness and gratitude. 
And let's not forget that he was the only one who Stuart Beal trusted to take 
care of NONMEM and bring it forward into 21st century.

Katya
On 8/2/2024 3:55 PM, Diane Mould wrote:
Dear All
I am very saddened to hear this news.  Tom Ludden was one of the nicest and 
smartest people that I have ever known.  He was a gentle giant in our field and 
I will miss him.
Best
Diane

From: owner-nmus...@globomaxnm.com<mailto:owner-nmus...@globomaxnm.com> 
<mailto:owner-nmus...@globomaxnm.com> On Behalf 
Of Riley, Steve
Sent: Friday, August 2, 2024 2:41 PM
To: nmusers@globomaxnm.com<mailto:nmusers@globomaxnm.com>
Subject: [External email][NMusers] Sad news about Dr. Ludden


CAUTION: This email originated from outside the organization. Do not click 
links or open attachments unless you recognize the sender and know the content 
is safe.
Dear NM-Users,

Regrettably, I am writing to let you know that Dr. Ludden passed away Tuesday 
evening, 30JUL2024.

I was able to get there over the weekend prior to visit him and his family.
During his wakeful moments we had some good scientific discussions.
We talked a lot about NONMEM and how its functionality and utility has expanded 
since he retired. He was pleased to hear about the changes.

He was surrounded by family for the days leading up to the end. They were all 
appreciative that I was able to get there and tell him (and them) how much he 
meant to all of us and the impact he had on our careers.

I think memories of Dr. Ludden were characterized perfectly by Marc Gastonguay, 
“I am forever grateful for the positive impact that Tom had on my life and 
career, not to mention the tremendous, although often underappreciated, 
contributions he made to the disciplines of clinical pharmacology and 
pharmacometrics. His humble brilliance will be missed and fondly remembered.”

Steve Riley

RE: [External email][NMusers] Sad news about Dr. Ludden

[Patel, Bela]

Public

Dear All,
I am extremely saddened to hear this news. As mentioned by Ene, Dr. Tom Ludden 
was one of the pioneers in advancing pharmacometrics along with Dr. Beal and 
Dr. Sheiner promoting its value and impact in drug discovery and development as 
well as acceptance by the FDA. He provided invaluable scientific advice and 
trained numerous scientists in pharmacometrics. He was a real gentle soul and 
it was truly a privilege to have known him and be tutored by him.

May his soul rest in peace.

Sincerely,
Bela

From: owner-nmus...@globomaxnm.com  On Behalf Of 
ENE ETTE
Sent: Friday, August 2, 2024 5:30 PM
To: Diane Mould ; Riley, Steve ; 
nmusers@globomaxnm.com
Subject: RE: [External email][NMusers] Sad news about Dr. Ludden

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EXTERNAL EMAIL– Use caution with any links or file attachments.
Dear All:
In Dr. Ludden we lost an excellent scientist who helped to revolutionize and 
advance clinical pharmacokinetics, pharmacometrics, clinical pharmacology, and 
drug development. I’m indebted to him for the impact he made on my life as a 
pharmacometrician, clinical pharmacologist, and drug developer while working 
with him at the FDA. He started the Pharmacometrics Staff Unit which became 
Pharmacometrics Division in later years.

May his soul rest in peace.

Sincerely,
Ene.

Sent from Mail<https://go.microsoft.com/fwlink/?LinkId=550986> for Windows

From: Diane Mould<mailto:drmo...@pri-home.net>
Sent: Friday, August 2, 2024 4:03 PM
To: Riley, Steve<mailto:steve.ri...@pfizer.com>; 
nmusers@globomaxnm.com<mailto:nmusers@globomaxnm.com>
Subject: RE: [External email][NMusers] Sad news about Dr. Ludden

Dear All
I am very saddened to hear this news.  Tom Ludden was one of the nicest and 
smartest people that I have ever known.  He was a gentle giant in our field and 
I will miss him.
Best
Diane

From: owner-nmus...@globomaxnm.com<mailto:owner-nmus...@globomaxnm.com> 
mailto:owner-nmus...@globomaxnm.com>> On Behalf 
Of Riley, Steve
Sent: Friday, August 2, 2024 2:41 PM
To: nmusers@globomaxnm.com<mailto:nmusers@globomaxnm.com>
Subject: [External email][NMusers] Sad news about Dr. Ludden


CAUTION: This email originated from outside the organization. Do not click 
links or open attachments unless you recognize the sender and know the content 
is safe.
Dear NM-Users,

Regrettably, I am writing to let you know that Dr. Ludden passed away Tuesday 
evening, 30JUL2024.

I was able to get there over the weekend prior to visit him and his family.
During his wakeful moments we had some good scientific discussions.
We talked a lot about NONMEM and how its functionality and utility has expanded 
since he retired. He was pleased to hear about the changes.

He was surrounded by family for the days leading up to the end. They were all 
appreciative that I was able to get there and tell him (and them) how much he 
meant to all of us and the impact he had on our careers.

I think memories of Dr. Ludden were characterized perfectly by Marc Gastonguay, 
“I am forever grateful for the positive impact that Tom had on my life and 
career, not to mention the tremendous, although often underappreciated, 
contributions he made to the disciplines of clinical pharmacology and 
pharmacometrics. His humble brilliance will be missed and fondly remembered.”

Steve Riley


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Re: [EXTERNAL] Re: [External email][NMusers] Sad news about Dr. Ludden

[Menon, Sujatha S]

Very sorry to hear this news.
He was a patient, kind and great teacher who went out of his way for his 
students!
May he rest in peace
Sujatha

On Aug 2, 2024, at 4:25 PM, Ekaterina Gibiansky  
wrote:



I second everything Steve, and Mark, and Diane said. All of us who were blessed 
to work alongside him will forever remember him with fondness and gratitude. 
And let's not forget that he was the only one who Stuart Beal trusted to take 
care of NONMEM and bring it forward into 21st century.

Katya

On 8/2/2024 3:55 PM, Diane Mould wrote:
Dear All
I am very saddened to hear this news.  Tom Ludden was one of the nicest and 
smartest people that I have ever known.  He was a gentle giant in our field and 
I will miss him.
Best
Diane

From: owner-nmus...@globomaxnm.com 
 On Behalf 
Of Riley, Steve
Sent: Friday, August 2, 2024 2:41 PM
To: nmusers@globomaxnm.com
Subject: [External email][NMusers] Sad news about Dr. Ludden



CAUTION: This email originated from outside the organization. Do not click 
links or open attachments unless you recognize the sender and know the content 
is safe.
Dear NM-Users,

Regrettably, I am writing to let you know that Dr. Ludden passed away Tuesday 
evening, 30JUL2024.

I was able to get there over the weekend prior to visit him and his family.
During his wakeful moments we had some good scientific discussions.
We talked a lot about NONMEM and how its functionality and utility has expanded 
since he retired. He was pleased to hear about the changes.

He was surrounded by family for the days leading up to the end. They were all 
appreciative that I was able to get there and tell him (and them) how much he 
meant to all of us and the impact he had on our careers.

I think memories of Dr. Ludden were characterized perfectly by Marc Gastonguay, 
“I am forever grateful for the positive impact that Tom had on my life and 
career, not to mention the tremendous, although often underappreciated, 
contributions he made to the disciplines of clinical pharmacology and 
pharmacometrics. His humble brilliance will be missed and fondly remembered.”

Steve Riley

RE: [External email][NMusers] Sad news about Dr. Ludden

[ENE ETTE]

Dear All:In Dr. Ludden we lost an excellent scientist who helped to revolutionize and advance clinical pharmacokinetics, pharmacometrics, clinical pharmacology, and drug development. I’m indebted to him for the impact he made on my life as a pharmacometrician, clinical pharmacologist, and drug developer while working with him at the FDA. He started the Pharmacometrics Staff Unit which became Pharmacometrics Division in later years. May his soul rest in peace. Sincerely,Ene. Sent from Mail for Windows From: Diane MouldSent: Friday, August 2, 2024 4:03 PMTo: Riley, Steve; nmusers@globomaxnm.comSubject: RE: [External email][NMusers] Sad news about Dr. Ludden Dear AllI am very saddened to hear this news.  Tom Ludden was one of the nicest and smartest people that I have ever known.  He was a gentle giant in our field and I will miss him.Best Diane  From: owner-nmus...@globomaxnm.com  On Behalf Of Riley, SteveSent: Friday, August 2, 2024 2:41 PMTo: nmusers@globomaxnm.comSubject: [External email][NMusers] Sad news about Dr. Ludden CAUTION: This email originated from outside the organization. Do not click links or open attachments unless you recognize the sender and know the content is safe. Dear NM-Users, Regrettably, I am writing to let you know that Dr. Ludden passed away Tuesday evening, 30JUL2024.I was able to get there over the weekend prior to visit him and his family. During his wakeful moments we had some good scientific discussions. We talked a lot about NONMEM and how its functionality and utility has expanded since he retired. He was pleased to hear about the changes.He was surrounded by family for the days leading up to the end. They were all appreciative that I was able to get there and tell him (and them) how much he meant to all of us and the impact he had on our careers. I think memories of Dr. Ludden were characterized perfectly by Marc Gastonguay, “I am forever grateful for the positive impact that Tom had on my life and career, not to mention the tremendous, although often underappreciated, contributions he made to the disciplines of clinical pharmacology and pharmacometrics. His humble brilliance will be missed and fondly remembered.”Steve Riley  

Re: [External email][NMusers] Sad news about Dr. Ludden

[Ekaterina Gibiansky]

I second everything Steve, and Mark, and Diane said. All of us who were 
blessed to work alongside him will forever remember him with fondness 
and gratitude. And let's not forget that he was the only one who Stuart 
Beal trusted to take care of NONMEM and bring it forward into 21st century.


Katya

On 8/2/2024 3:55 PM, Diane Mould wrote:


Dear All

I am very saddened to hear this news.  Tom Ludden was one of the 
nicest and smartest people that I have ever known.  He was a gentle 
giant in our field and I will miss him.


Best

Diane

*From:*owner-nmus...@globomaxnm.com  *On 
Behalf Of *Riley, Steve

*Sent:* Friday, August 2, 2024 2:41 PM
*To:* nmusers@globomaxnm.com
*Subject:* [External email][NMusers] Sad news about Dr. Ludden




*CAUTION:*This email originated from outside the organization. Do not 
click links or open attachments unless you recognize the sender and 
know the content is safe.


Dear NM-Users,

Regrettably, I am writing to let you know that Dr. Ludden passed away 
Tuesday evening, 30JUL2024.


I was able to get there over the weekend prior to visit him and his 
family.


During his wakeful moments we had some good scientific discussions.

We talked a lot about NONMEM and how its functionality and utility has 
expanded since he retired. He was pleased to hear about the changes.


He was surrounded by family for the days leading up to the end. They 
were all appreciative that I was able to get there and tell him (and 
them) how much he meant to all of us and the impact he had on our careers.


I think memories of Dr. Ludden were characterized perfectly by Marc 
Gastonguay, “I am forever grateful for the positive impact that Tom 
had on my life and career, not to mention the tremendous, although 
often underappreciated, contributions he made to the disciplines of 
clinical pharmacology and pharmacometrics. His humble brilliance will 
be missed and fondly remembered.”



Steve Riley

RE: [External email][NMusers] Sad news about Dr. Ludden

[Diane Mould]

Dear All
I am very saddened to hear this news.  Tom Ludden was one of the nicest and 
smartest people that I have ever known.  He was a gentle giant in our field and 
I will miss him.
Best
Diane

From: owner-nmus...@globomaxnm.com  On Behalf Of 
Riley, Steve
Sent: Friday, August 2, 2024 2:41 PM
To: nmusers@globomaxnm.com
Subject: [External email][NMusers] Sad news about Dr. Ludden


CAUTION: This email originated from outside the organization. Do not click 
links or open attachments unless you recognize the sender and know the content 
is safe.
Dear NM-Users,

Regrettably, I am writing to let you know that Dr. Ludden passed away Tuesday 
evening, 30JUL2024.

I was able to get there over the weekend prior to visit him and his family.
During his wakeful moments we had some good scientific discussions.
We talked a lot about NONMEM and how its functionality and utility has expanded 
since he retired. He was pleased to hear about the changes.

He was surrounded by family for the days leading up to the end. They were all 
appreciative that I was able to get there and tell him (and them) how much he 
meant to all of us and the impact he had on our careers.

I think memories of Dr. Ludden were characterized perfectly by Marc Gastonguay, 
"I am forever grateful for the positive impact that Tom had on my life and 
career, not to mention the tremendous, although often underappreciated, 
contributions he made to the disciplines of clinical pharmacology and 
pharmacometrics. His humble brilliance will be missed and fondly remembered."

Steve Riley