Within the Biomedical Research Institute (BIOMED)  of Hasselt University, the 
following position (m/f) is available:

PhD student in biomedical sciences (2x2 years) ‘Autoimmunity’:  Biomarker 
research in Multiple Sclerosis and Rheumatoid Arthritis
(mandate MBW/2008/021-HO)

Background
The Biomedical Research Institute (www.biomed.uhasselt.be) is a  
multidisciplinary research institute of the Hasselt University. 70  researchers 
and technical personnel perform molecular and cellular  biomedical research. 
The research is focused on two main research  domains: neuroinflammation and 
development of biosensors (in cooperation  with the Institute for Material 
Research (IMO)). 

Job description
The successful applicant will be involved in a research project entitled  ‘New 
diagnostic and prognostic antibody biomarkers for multiple  sclerosis (MS) and 
rheumatoid arthritis (RA)’ of the Biomedical Research  Institute (BIOMED) at 
Hasselt University. This project is aimed at  identifying a panel of new 
molecular target antigens combined with  existing target antigens selected on 
MS with diagnostic and prognostic  potency by using technological platforms 
that allow for profiling the  antibody reactivity to tissue antigens in these 
diseases. The first goal  is aimed at identifying new serum markers for MS and 
RA by a systematic  profiling of the humoral immune response using the powerful 
molecular  SAS technology. A second goal is aimed at studying the functional  
relevance of the existing selected MS markers and new MS and RA serum  markers 
in relation to disease by studying their expression in diseased  tissue and by 
studying T cell reactivity to
 these antigens. A third goal  is aimed at developing a high throughput and 
label free screening  platform using phages expressing autoantigens or derived 
peptide  fragments to efficiently validate candidate markers in a large number 
of  patients. The candidate will work on the third goal of the project.

Profile and diploma
The applicant should hold a master degree in biomedical sciences,  
bioengineering, biochemistry, biology, biotechnology, medicine,  chemistry, or 
equal). Students in their last master year can also apply.

Further information
        * Content job responsibilities: 
        * prof. dr. Piet Stinissen, +32-11-26 92  04, [EMAIL PROTECTED] 
        * prof. dr. Veerle Somers, +32-11-26 92  02, [EMAIL PROTECTED] 
        * prof. dr. Luc Michiels, +32-11-26 92 31, [EMAIL PROTECTED] 
        * fax +32 11 26 92 09, website: www.biomed.uhasselt.be 
        * Content terms of employment and selection  procedure: Jef Vanvoorden, 
011-26 80 80, [EMAIL PROTECTED] 
Application
Applicants must use the official application forms 
        * which are available at the Rectoraat of  Hasselt University, Campus 
Diepenbeek, Agoralaan - building D,  B-3590 Diepenbeek (Belgium), phone +32 - 
11 - 26 80 03 
        * or which can be downloaded here pdf-file / Word format. 
The completed application forms must reach the above mentioned address  no 
later than October 8th, 2008.
Application by e-mail will only be taken into consideration when sent to the 
following address: [EMAIL PROTECTED]


      

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