We run Pyramid via uwsgi, behind an OpenResty server (Nginx fork with
embedded lua interpreter).
IMHO the "best" stack is somewhat dependent on your application. We have a
large application and the forking model of uwsgi - combined with many of
its management hooks - lets us aggressively
100% with you. That's why I wrote it isn't "really" possible. It is
possible, just under limited conditions. IIRC, one could also use the COMET
chunking technique to faciliate this - though that would likely cause some
client side issues. If you're doing a direct browser-to-server connection,