I noticed something like this but I think it's usually triggered by
something in dom0. Most notably I have a finicky power button and I get the
reset/logout/shutdown dialog. When I hit escape to make it go away, I have
to change virtual screens back and forth as you described.
On Mon, Jun 5, 2023
I often experience clicks that get lost "in the void" meaning that the
actual xfce windows does not seem to receive them.
Typical example: I use firefox, and a noscript pop-up ("load
anonymously") with a button to click on: but I can't. What helps then,
is changing the virtual screen (go away)