Hi, my name is Marcel R. Lopes. My problem is,
I made a code to calculate the estimates of a Cox model with random effects.
Used to optimize the R command for this. The estimates were calculated
correctly, but the Hessian matrix does not have good values. The same thing
was done in SAS and gave good results for the Hessian Matrix. Where is the
problem in R? As the Hessian is calculated?. How could I solve this
problem?. I would be grateful if you could help me ....
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