Re: [R] How to represent the effect of one covariate on regression results?

2020-09-15 Thread Ana Marija
Hi David, thanks for the useful insight I did of course wrote to plink user group but no answer there. I guess they are more concerned about how to run commands with plink as oppose to interpret results. What I can tell about my cohort is that about 80% of cases had Type 2 diabetes while about

Re: [R] How to represent the effect of one covariate on regression results?

2020-09-15 Thread David Winsemius
On 9/15/20 8:57 AM, Ana Marija wrote: Hi Abby and David, Thanks for the useful tips! I will check those. I completed the regression analysis in plink (as R would be very slow for my sample size) but as I mentioned I need to determine the influence of a specific covariate in my results and

Re: [R] How to represent the effect of one covariate on regression results?

2020-09-15 Thread Abby Spurdle
> My question is how do I present/plot the effect of covariate "TD" in > the example it has "P" equal to 3.32228e-12 for all IDs in the > resulting file so that I show how much effect covariate "TD" has on > the analysis. Should I run another regression without covariate "TD" I'll take a second

Re: [R] How to represent the effect of one covariate on regression results?

2020-09-15 Thread Ana Marija
Hi Abby and David, Thanks for the useful tips! I will check those. I completed the regression analysis in plink (as R would be very slow for my sample size) but as I mentioned I need to determine the influence of a specific covariate in my results and Plink is of no help there. I did Pearson

Re: [R] How to represent the effect of one covariate on regression results?

2020-09-15 Thread David Winsemius
There is a user-group for PLINK, easily found by looking at the page you cited. This is not the correct place to submit such questions. https://groups.google.com/g/plink2-users?pli=1 -- David. On 9/14/20 6:29 AM, Ana Marija wrote: Hello, I was running association analysis using --glm

Re: [R] How to represent the effect of one covariate on regression results?

2020-09-14 Thread Abby Spurdle
I'm wondering if you want one of these: (1) Plots of "Main Effects". (2) "Partial Residual Plots". Search for them, and you should be able to tell if they're what you want. But a word of warning: Many people (including many senior statisticians) misinterpret this kind of information. Because,

[R] How to represent the effect of one covariate on regression results?

2020-09-14 Thread Ana Marija
Hello, I was running association analysis using --glm genotypic from: https://www.cog-genomics.org/plink/2.0/assoc with these covariates: sex,age,PC1,PC2,PC3,PC4,PC5,PC6,PC7,PC8,PC9,PC10,TD,array,HBA1C. The result looks like this: #CHROMPOSIDREFALTA1TESTOBS_CT