e that due to childcare requirements during the Covid lockdown I am
generally not available after 4pm.
From: aw7
Date: Friday, 12 June 2020 at 14:40
To: Keiran Raine
Cc: "samtools-help@lists.sourceforge.net"
Subject: Re: [Samtools-help] markdup "-c" option [EXT]
Hi Keiran,
Hi Keiran,
The -c option clears the duplicate flag and removes any 'dt' or 'do'
tags on a read prior to duplicate marking. I added it by request so
that a mix of duplicate marking programs did not give inconsistent
results.
There is no performance advantage, markdup does not take into account
Hi,
Can someone clarify the behaviour of "Clear previous duplicate settings and
tags" please?
If data has been duplicate marked at the "lane" level and then merged and
passed into markdup again, should this be in use? Does it give performance
advantage by reusing previous information?
Thanks
