大家好。我尝试用Bioconductor镜像使用帮助里的说明修改.Rprofile文件,但在我的主目录下没有找到这个文件,我手动建了一个但好像没有效果。Windows下我修改了R安装路径下的Rprofile.site,在安装包时会提示从清华镜像去寻找,但显示无法连接,提示无网络连接。

Bioconductor官网上的安装包方法是:
source("https://bioconductor.org/biocLite.R";)
biocLite("DESeq2")

所以我的问题是:
1.当换成清华镜像后,安装命令需要改变么?
2.Linux下如何设置源?

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