TweeterLookup.com did this email to twitter id lookup but has since closed down.
I dont think twitter exposes this functionality in the search api and you cannot search by email id. But there are third party providers available that might have this data. Try the Flowtown API or Rapleaf API. http://blog.rapleaf.com/dev/2010/01/04/person-api-v3/ ~~~ Mohan Arun ~~~ -- Twitter developer documentation and resources: http://dev.twitter.com/doc API updates via Twitter: http://twitter.com/twitterapi Issues/Enhancements Tracker: http://code.google.com/p/twitter-api/issues/list Change your membership to this group: http://groups.google.com/group/twitter-development-talk