I've been having the same issue since building a new system a couple months ago. The frequency is inconsistent, but rarely happens more than once per day. Sometimes I'll lose my keyboard mid-sentence, and other times I won't be able to unlock the system in the morning.
Oddly, my USB mouse (a Razer Naga) always still works, and the side buttons which act as a number pad also always work. However, by USB hub loses power, and neither it nor my keyboard ever regain power or functionality when re-plugging or switching ports. It's always fixed by a reboot. I'm on a Threadripper 3990x with an ASUS ROG Zenith II Extreme motherboard. Here's the snippet from /var/log/syslog: Jan 14 19:37:19 amaranth systemd[1]: fprintd.service: Succeeded. Jan 14 19:38:44 amaranth kernel: [37857.592954] xhci_hcd 0000:49:00.3: Mismatch between completed Set TR Deq Ptr command & xHCI internal state. Jan 14 19:38:44 amaranth kernel: [37857.592957] xhci_hcd 0000:49:00.3: ep deq seg = 000000003ccd0405, deq ptr = 000000006daebfd1 Jan 14 19:38:45 amaranth kernel: [37858.593779] xhci_hcd 0000:49:00.3: AMD-Vi: Event logged [IO_PAGE_FAULT domain=0x0035 address=0x0 flags=0x0000] Jan 14 19:38:50 amaranth kernel: [37863.667171] xhci_hcd 0000:49:00.3: xHCI host not responding to stop endpoint command. Jan 14 19:38:50 amaranth kernel: [37863.667178] xhci_hcd 0000:49:00.3: xHCI host controller not responding, assume dead Jan 14 19:38:50 amaranth kernel: [37863.667220] xhci_hcd 0000:49:00.3: HC died; cleaning up Jan 14 19:38:50 amaranth kernel: [37863.667255] usb 9-3: USB disconnect, device number 2 Jan 14 19:38:50 amaranth kernel: [37863.667258] usb 9-3.1: USB disconnect, device number 4 Jan 14 19:38:50 amaranth kernel: [37863.667447] usb 10-3: USB disconnect, device number 2 Jan 14 19:38:50 amaranth kernel: [37863.667449] usb 10-3.2: USB disconnect, device number 4 Jan 14 19:38:50 amaranth kernel: [37863.667451] usb 10-3.2.4: USB disconnect, device number 5 Jan 14 19:38:50 amaranth kernel: [37863.668402] usb 10-4: USB disconnect, device number 3 Jan 14 19:38:50 amaranth kernel: [37863.735579] usb 9-3.2: USB disconnect, device number 6 Jan 14 19:38:50 amaranth kernel: [37863.735581] usb 9-3.2.3: USB disconnect, device number 7 Jan 14 19:38:50 amaranth acpid: input device has been disconnected, fd 17 Jan 14 19:38:50 amaranth acpid: input device has been disconnected, fd 8 Jan 14 19:38:50 amaranth acpid: input device has been disconnected, fd 9 Jan 14 19:38:50 amaranth kernel: [37863.979627] usb 9-3.2.4: USB disconnect, device number 9 Jan 14 19:38:50 amaranth kernel: [37863.979630] usb 9-3.2.4.4: USB disconnect, device number 10 Jan 14 19:38:50 amaranth kernel: [37864.076604] usb 9-4: USB disconnect, device number 3 Jan 14 19:38:50 amaranth kernel: [37864.076833] usb 9-5: USB disconnect, device number 5 Jan 14 19:38:50 amaranth acpid: input device has been disconnected, fd 7 Jan 14 19:38:50 amaranth acpid: input device has been disconnected, fd 10 Jan 14 19:38:50 amaranth kernel: [37864.231560] usb 9-6: USB disconnect, device number 8 Jan 14 19:38:50 amaranth acpid: input device has been disconnected, fd 11 Jan 14 19:38:50 amaranth acpid: input device has been disconnected, fd 12 -- You received this bug notification because you are a member of Ubuntu Bugs, which is subscribed to Ubuntu. https://bugs.launchpad.net/bugs/1908894 Title: USB controllers disconnects after random time To manage notifications about this bug go to: https://bugs.launchpad.net/ubuntu/+source/linux/+bug/1908894/+subscriptions -- ubuntu-bugs mailing list ubuntu-bugs@lists.ubuntu.com https://lists.ubuntu.com/mailman/listinfo/ubuntu-bugs