Most of my domains in /var/vpopmail/domains/ have a .qmail-default file that
looks like this:
| /var/vpopmail/bin/vdelivermail '' bounce-no-mailbox
After upgrading from vpopmail 5.4.19 to 5.4.26, any user that was created
using QmailAdmin 1.2.10 that did NOT have the Spam Detection box
I've never run into that behaviour before. A .qmail in a users directory is not
required. I would recommend reverting back to your old version and do some
testing on a development box, virtual machine, or whatever you can test this on.
Perhaps also post more details about your environment, like