http://pubs.acs.org/cen/newscripts/89/8923newscripts.html
Coming in over the transom the other day was a letter, not an e-mail, from Charles V. Johnson of Lake Geneva, Wis., touting the discovery that earwax is an OXIDATIVE ORGANOCATALYST. Working with his chemistry set as a kid circa 1960, Johnson would mix water, sodium silicate, and cobalt or other metal salts to make colorful lake pigments, he tells Newscripts. He serendipitously found that his earwax seemed to accelerate the process. Johnson and a friend used the pigments to touch up scratches on appliances in a store that his buddy’s father owned. Later on, as a zoology undergraduate student at the University of Wisconsin, Madison, Johnson took a daring chance in a chemistry lab: He substituted earwax applied to a boiling chip for a palladium catalyst in an organic synthesis experiment. It worked well to make all-trans-stilbene, although his professor didn’t seem impressed. “That’s the thing that has bothered me most,” Johnson says. “My instructors didn’t think there was anything to it.” After graduating, Johnson worked as a chemical technician at Sigma-Aldrich; he is now retired. He has toyed with a few other attempts to use earwax as a catalyst over the years. For example, Johnson was at his dentist’s office last year and was inspired to try an experiment making a filling. He took methacrylate-based material commonly used in dentistry, added a touch of earwax, and it seemed to work well to polymerize the methacrylate. “It hardened right up,” he says. Johnson has contemplated what the active catalyst might be in earwax, but he hasn’t been able to do an analysis to find out. Most likely it’s a protein or amino acid, he believes, or possibly a lipid. Organocatalysts typically are biomolecules such as the amino acid proline or a synthetic catalyst such as an imidazolidinone. “Once we find out what the compound is, it could be treated like a natural product and synthesized in larger amounts,” he proposes. “I’d like to think it could be worth a lot.” But to the point of his letter: “I consider this catalyst unique and worry that the chemical industry will not develop it into a product,” Johnson laments. “I see a lot of retrogressive technology. I hope this will not fall into that category.” <end>
