Re: [Vo]:Good news about the pandemic at last

2020-11-19 Thread Michael Foster
Interesting info, Jed. Thanks.

I hope these vaccines are effective, not because they need to be, but because 
it will calm down the unnecessary panic over this relatively low risk virus. 
There are no reliable statistics about the virus. False positives and negatives 
abound. The CDC itself has said only about 6% of reported mortality could 
reliably be attributed to the virus. When you take that into account, the 
common cold probably has a higher mortality rate. 

Big Pharma will get its payday out of this nonsense and more effective 
treatments and preventatives will continue to be suppressed or ignored.  
Incidentally, I notice that doctors have finally gotten around to using 
nebulized n-acetyl cysteine as a treatment, which was a standard procedure for 
viral pneumonia for years. What the hell took so long? Not enough money in it 
for Big Pharma? People died from lack of this treatment, an effective mucolytic 
and anti-viral.

The probable very high mortality rate in the virus' country of origin is likely 
due to genetic factors and the fact that on the order of 50% to 60% of men 
there smoke. The the stats in northern Italy are interesting because you can't 
find out how many of the reported cases are from illegal alien workers from the 
virus' city of origin. 

Just for fun, read this: 
https://www.google.com/url?q=https://www.creators.com/read/michelle-malkin=U=2ahUKEwi54cnf3I_tAhUEpp4KHUnXBTkQFjAAegQIABAB=AOvVaw1pLcfX-m4KL3QD7e3KPVuG

This woman is a notorious anti-vaxxer, but read it anyway, for another point of 
view.





 On Monday, November 16, 2020, 07:58:58 PM UTC, Jed Rothwell 
 wrote:





 I realize this is off topic. And I expect everyone here has heard about it. 
But I thought you would like to see some quantitative information.
Here is a note on temperatures. The second article says the Moderna vaccine can 
be kept at -20°C. The Pfizer vaccine has to be kept at -75°C during shipping 
and storage. It can be stored in an ordinary refrigerator for up to 5 days 
before it is used. (https://www.bbc.com/news/technology-54889084) I asked a 
nurse about this. She said there are several vaccines that require cold 
storage. She said this will probably come as a powder, which is mixed with room 
temperature fluid before inoculation. The older version of the shingles vaccine 
was like this.




Good news! Moderna's vaccine is reportedly 95% effective. Here are the raw 
numbers as reported by CNN:




15,000 vaccines administered. 5 people in that group got COVID-19. They had 
mild cases.

15,000 placebos administered. 90 people in that group got COVID-19. 11 had 
severe cases.




This is reported as 94.5% effective, which I think is too many digits of 
precision. I would say >90%. But I quibble. I think there is no question it is 
effective.




It seems the vaccine reduces the severity of the disease when it does not 
prevent it completely




There were no severe side effects. There were some side effects in some 
patients, such as headaches.




Fauci said this is good news. If the Pfizer and or the Moderna vaccines are 
approved, the first ones may be administered in December to risk groups such as 
doctors and nurses. Fauci predicted the general population may be vaccinated 
from May to July 2021.




https://www.nytimes.com/2020/11/16/health/Covid-moderna-vaccine.html





"Early Data Show Moderna’s Coronavirus Vaccine Is 94.5% Effective






Moderna is the second company to report preliminary results from a large trial 
testing a vaccine. But there are still months to go before it will be widely 
available to the public."







More good news, from CNN. This may drive down the stock market value of Pfizer:




While the two vaccines appear to have very similar safety and efficacy 
profiles, Moderna's vaccine has a significant practical advantage over Pfizer's.




Pfizer's vaccine has to be kept at minus 75 degrees Celsius — or about minus 
103 degrees Fahrenheit. No other vaccine in the US needs to be kept that cold, 
and doctors' offices and pharmacies do not have freezers that go that low.




Moderna's vaccine can be kept at minus 20 degrees Celsius, which is about minus 
4 degrees Fahrenheit. Other vaccines, such as the one against chickenpox, need 
to be kept at that temperature.




That means Moderna's vaccine can be kept in "a readily available freezer that 
is available in most doctors' offices and pharmacies," said Dr. Tal Zacks, 
Moderna's chief medical officer. "We leverage infrastructure that already 
exists for other marketed vaccines."




Another advantage of Moderna's vaccine is that it can be kept for 30 days in 
the refrigerator, the company announced Monday. Pfizer's vaccine can last only 
five days in the refrigerator.



[Vo]:PLOS Writing Center guide to writing and publishing papers

2020-11-19 Thread Jed Rothwell
Someone from PLOS sent me a form letter addressed to Dr. Rothwell,
suggesting I visit their online guide to writing and publishing scientific
papers. I do not know whether to take that as a compliment or an insult. I
would like to think it means they are reading the JCMNS and other papers.
Anyway, their guide is pretty good:

https://plos.org/resources/writing-center/

"The PLOS Writing Center is your guide to preparing a successful manuscript.

Drawn from the cumulative expertise of researchers, professional scientific
editors, and journal staff, the Writing Center offers detailed, practical
guidance for writing each section of a research article."

It has various suggestions such as "do not use an acronym in the abstract."
And, "when you mention something in the abstract, be sure you discuss it in
the paper."


Regarding acronyms --

When I copy edit papers I often nitpick the use of acronyms. Here are the
rules I learned in high school. The first time an acronym appears in the
paper you should define it. Widely used technical terms come first with the
definition in parenthesis "SEM (scanning electron microscope)." Terms that
we use in this field that people outside the field may not know might be
presented in the opposite order: "cold fusion (CF)," "Fleischmann and Pons
(F)," "nuclear active environment (NAE)."

When a term is only used once or twice in a paper, I suggest you forgo the
use of the acronym. Just spell out "nuclear active environment" every time
you use it. It is a burden on the reader having to remember what the
acronym stands for.

"SEM" is so widely used, everyone knows what it means and most people refer
to it by the acronym, so perhaps you do not need to define that one. You
can use it even if it only appears once or twice.