Yes.  See:

The Infrastructure Forum of the U.K. has warned that "out of office"
auto-replies are used by thieves to target empty houses. The thieves
purchase lists of e-mail addresses and mass-mail the list, hoping to
receive "out of office" responses. Criminals then cross-reference the
e-mail address to online directories to discover names, addresses, and
phone numbers.  More than 120 warnings about the scam were received by
the Corporate IT Forum.

full article at http://www.vnunet.com/News/1137316 

Rodel Calvario wrote:
> 
> Hello All,
> 
> Don't know if this is the right place to post this. Are the out of office
> messages inviting hackers to attack your corporate network? Is this a risk
> to your company if employees start using the Out of Office feature?
> 
> Any comments?
> 
> Thanks in adavnce.
> 
> Rodel
> 
> _________________________________________________________________
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-- 
James W. Meritt CISSP, CISA
Booz | Allen | Hamilton
phone: (410) 684-6566

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