Hi Joan,

My views (for what they're worth):


   - Key issue is ScvO2 as sole indicator of O2 delivery. Agree other
   modalities of assessment of volume responsiveness and O2 delivery have
   equal or greater role, but I believe answer lies in a colleciton of
   clinical information: dangerous for anyone to run too fast with a single
   modality!
   - CVC is necessary for a majority of these patients for pressors/ tropes
   anyway. The authors don't argue against CVC but against over-reliance on
   CVP and ScvO2. Pragmatically, we need to build a larger picture: we
   assimilate informaiton from multiple sources to build our picture
   - Slight concerns with article. It confuses septic shock with severe
   sepsis which is not helpful or appropriate (see criteria fig 1).
   Referencing is somewhat author-centric


*Summary*: Don't let this hold you back. EDs get excited about EGDT and
forget the basics. Let's try not to get hung up on individual modalities
(esp until we have ARISE/ ProCESS/ ProMISe) but recognise and intervene
quickly using the monitoring strategies we have to hand and an assimilation
of information. Rivers' protocol is good- and prob better than random care-
but no-one ever suggested it was the ultimate answer!

What do others think?

kind regards

Ron

On Mon, Dec 12, 2011 at 4:37 AM, Joan Greene <[email protected]> wrote:


> Has anyone else received push-back in their early goal-directed therapy
> protocols after the attached article was published?  We recently
> implemented the SSC guidelines for EGDT in our hospital by using a
> screening algorithm to activate a sepsis response team.  The response team
> follows the 6-hour bundle.  Now, we have some physicians who want to
> revisit the need for a central line based on this article.  The bundle
> cannot be followed without a central line to measure the CVP and/or ScvO2
> monitoring.  I would appreciate any comments.  Thank you.
>
> Joan Greene
> San Diego
>


-- 
Dr Ron Daniels


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