The cost savings came from reducing the frequency of the dosing.

Terry P. Clemmer, MD
Director of Critical Care Medicine
LDS Hospital
8th Ave and 'C' Street
Salt Lake City, Utah 84143

Phone 801-408-3661
E-mail: [email protected]<mailto:[email protected]>


"Confidential Report for Improvement of Hospital, Facility and Patient 
Care--Not Part of Medical Record and Not to be Used in Litigation--Prepared 
Pursuant to Utah Code Ann. § 26-25-1 et seq., or Idaho Code Ann. § 39-1392 et 
seq."

From: Richard Teplick [mailto:[email protected]]
Sent: Thursday, June 07, 2012 9:14 AM
To: Terry Clemmer; 'Shawver, Stephanie'; [email protected]
Subject: RE: [Sepsis Groups] Extended Infusion Beta Lactam Antibiotics

I agree.  The data in animal data and especially the concept that maintaining 
levels above the MIC for  antibiotics with time-dependent killing are both 
compelling but the human studies have been mixed and generally unconvincing.  
How does infusion save money?

From: 
[email protected]<mailto:[email protected]>
 
[mailto:[email protected]]<mailto:[mailto:[email protected]]>
 On Behalf Of Terry Clemmer
Sent: Wednesday, June 06, 2012 12:00
To: Shawver, Stephanie; 
[email protected]<mailto:[email protected]>
Subject: Re: [Sepsis Groups] Extended Infusion Beta Lactam Antibiotics

Stephanie
When I read the literature carefully the evidence that it improves outcome is 
soft at best. That being said, in the Urban Central Region of Intermountain 
Healthcare we have gone to extended infusion of Vancomycin despite the 
inadequacy of the evidence that it saves lives because it financially made a 
difference in the cost.

Terry P. Clemmer, MD
Director of Critical Care Medicine
LDS Hospital
8th Ave and 'C' Street
Salt Lake City, Utah 84143

Phone 801-408-3661
E-mail: [email protected]<mailto:[email protected]>


"Confidential Report for Improvement of Hospital, Facility and Patient 
Care--Not Part of Medical Record and Not to be Used in Litigation--Prepared 
Pursuant to Utah Code Ann. § 26-25-1 et seq., or Idaho Code Ann. § 39-1392 et 
seq."

From: 
[email protected]<mailto:[email protected]>
 
[mailto:[email protected]]<mailto:[mailto:[email protected]]>
 On Behalf Of Shawver, Stephanie
Sent: Friday, June 01, 2012 3:55 PM
To: 
[email protected]<mailto:[email protected]>
Subject: [Sepsis Groups] Extended Infusion Beta Lactam Antibiotics

Colleagues,

I am curious to hear feedback on the recent studies indicating that extended or 
continuous infusion of certain beta-lactam antibiotics have shown better 
outcomes for severe sepsis and septic shock patients. Our hospital's Sepsis 
Committee is considering changing the antibiotic regime on our protocol to have 
the applicable beta-lactam antibiotics infused over an extended period of time, 
if not continuous. Are there any other facilities out there going this route?

Stephanie Shawver BSN, RN
Infection Prevention Practitioner & SLMV Sepsis Coordinator
St. Luke's Magic Valley
801 Pole Line Road West  | Twin Falls, ID 83301
Office: (208) 814.3052   |  Email: 
[email protected]<mailto:[email protected]>
Infection Prevention Line: (208)-814-5120
" We are what we repeatedly do. Excellence then, is not an act but a habit." - 
Aristotle


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