And yet due to a paucity of data for this assessment method in the septic shock 
cohort there remains no recommendation by experts in the new guidelines.
Mary Ann Daly
Regional Clinical Initiative Lead
GBMF Grant
916.200.5604

From: Tom Ahrens [mailto:[email protected]]
Sent: Monday, August 20, 2012 07:25 AM
To: [email protected] <[email protected]>; Mulligan, Ann W.
Cc: [email protected] <[email protected]>
Subject: Re: [Sepsis Groups] Heart failure patients presenting with sepsis

This is an important question Ann.  The research literature has focused on 
measuring traditional parameters in sepsis resuscitation, despite evidence 
these parameters suffer from failing to adequately reflect volume status and 
are often slow to change (CVP being one of the worst offenders).  More accurate 
assessments with ultrasound, both flow and image, are able to give a better 
idea of adequacy of resuscitation.  Measures such as stroke volume response and 
echo images of EF are likely, in my opinion, to replace most current measures 
that are used to guide resuscitation.  These parameters just need to be better 
studied in sepsis.  Their value in the perioperative and trauma settings, 
particularly stroke volume optimization, are well supported in research.
Tom

Tom Ahrens PhD RN FAAN


-----Original Message-----
From: George Kramer <[email protected]>
To: Mulligan, Ann W. <[email protected]>
Cc: Sepsis list group ([email protected]) 
<[email protected]>
Sent: Mon, Aug 20, 2012 8:39 am
Subject: Re: [Sepsis Groups] Heart failure patients presenting with sepsis

Ann,

important question. I am just an observer of sepsis care, but this always seems 
to be a discussion with uncertain resolution.  often leading to delays in 
therapy.

ultrasound assessment of filling and contraction - diastolic and systolic 
function, would likely help decide when to give fluid to CHF patients as well 
as those with other co-morbidities or even most septic patients after 
substantial fluid.  When should drugs be administered and when should fluid be 
continued. etc.

Can echo be performed by an attending ICU doc, resident, nurse or does this 
require a cardiology consult?

g


George C Kramer, PhD
Director, Resuscitation Research Lab
Professor, Dept. of Anesthesiology
301 University Blvd.
UTMB, Galveston, TX 77555-1102

Office (Mary) 409-747-0077
Direct: 409-772-3969
Cell: 409-939-3040
Lab (Muzna) 409-772-6885
Fax:    409-772-8895
email: [email protected]
http://www.utmb.edu/rrl/

On Aug 17, 2012, at 12:13 PM, Mulligan, Ann W. wrote:

Our hospital continues to struggle with meeting the fluid bolus requirements 
when a CHF patient with a low EF presents with sepsis.  Cardiology is 
suggesting that ED perform a bedside ECHO if the patient has CHF and/or know 
reduced ejection fraction, and to be prudent when giving several liters of 
fluid.

How are other hospitals approaching these patients, and what is the latest 
guidelines for sepsis treatment within this diagnosis?
Ann Mulligan, RN, BSN, CPHQ
Manager Quality & Outcomes
Alta Bates Summit Medical Center
2450 Ashby Ave.
Berkeley, CA  94705
Ph: (510) 204-2986
Fax: (510) 204-1221
Cell: (510) 325-4044
[email protected]
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