Hello, I attended a sepsis lecture yesterday at NJHA.  It was very informative. 
 I have a question related to stacking vs concurrent antibiotic administration 
within the 1st hour of calling a sepsis alert.  I am an educator at Kennedy 
University Hospital & we are re visiting our sepsis policy.  The nurses and 
physicians seem to be at a standstill as to how fast to give the antibiotics 
within the 1st hour.  I have not noted any literature related to administering 
all of the antibiotics through different lines (or central lines) or whether to 
stack in this "tissue code" situation.  Can you comment? There is a pharmacist 
view of the IgE theory that one will not experience an allergic reaction until 
the 3rd or 4th dose and therefore the antibiotics should be administered at the 
same time in different IV sites and not be concerned related to an allergic 
reaction (and also that there is so much IVF being given that a reaction would 
be flushed through?)


Lea Ann Kellum, MSN, RN, CCRN
Clinical Educator, Critical Care
Department of Clinical Education and Research
Kennedy University Hospital
Cherry Hill Campus
Office  856-488-6790
Cell     856-298-8785
Email:  [email protected]



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