Hello, I am a 4th year medical student at UCSF who has been involved with a long term project working on immunomodulation in sepsis.
I have become increasingly interested in the "surviving sepsis campaign" and its affect on mortality. Specifically, I am interested in when (early or late) US patients are succumbing to septic insult. Given the ongoing debate as to whether research/clinical trials should focus on suppressing the early hyper-inflammatory state or focus on ramping up later immunosuppression I began to search out data for US patients. That is to say, "which phase of the disease process results in most mortality?" I imagine that the surviving sepsis campaign has significantly changed not only mortality rates but also the chronicity of that mortality. I have searched extensively throughout the literature but have found neither historical nor contemporary data to answer this question. Thank you in advance for any insight you may have regarding this data, Oliver Bellevue, MS4 UCSF SOM
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