Re: IV push antibiotics,
Most of the beta lactams can be given as rapid infusions, there are many others 
like quinolones, vanco, which cannot be given by rapid infusion. IV push may be 
an option for some antibiotics, not sure where your pay for performance would 
look to find documentation of when the dose had been totally infused.


Daniel Gerard RPh
Critical Care Pharmacist
McClaren-Northern Michigan
Phone: 231-487-4770
FAX: 231-487-4817
[email protected]

 

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Sent: Friday, February 14, 2014 3:08 PM
To: [email protected]
Subject: Sepsisgroups Digest, Vol 96, Issue 8

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Today's Topics:

   1. Re: LR vs NS for fluid (Jenkins, Bill)
   2. Severe Sepsis and Meningitis (Joseph Clement)


----------------------------------------------------------------------

Message: 1
Date: Thu, 13 Feb 2014 14:50:45 +0000
From: "Jenkins, Bill" <[email protected]>
To: "[email protected]"
        <[email protected]>
Subject: Re: [Sepsis Groups] LR vs NS for fluid
Message-ID:
        <90d27045f7498c48b992c582be857ede4e209...@whvmexmbx2.excelahealth.org>
Content-Type: text/plain; charset="us-ascii"

Good morning!

Does anyone have any info regarding IV push antibiotics for first dose 
antibiotic dosing in the ED. We are challanged by some of our payers quality 
"pay for performance" programs in PA to start and COMPLETE first dose 
antibiotics within 3 hours of arrival. Our health system has some fairly 
conservative infusion timing guidelines for nursing  - any ideas or resources 
are appreciated! 

William Jenkins, MD
Excela Health
Emergency Medicine
Pennsylvania

 

________________________________________
From: [email protected] 
[[email protected]] on behalf of Kramer, George C. 
[[email protected]]
Sent: Thursday, February 13, 2014 9:02 AM
To: Daniel Gerard; [email protected]
Subject: Re: [Sepsis Groups] LR vs NS for fluid

Daniel,

I sent this answer out to the group regarding a question on colloid use.


A perspective of a physiologist,

One to three is the classic crystalloid to colloid ratio and probably good to 
use for equivalent volume expansion of colloid to crystalloid. But crystalloid 
expansion is quite transient and colloids are more sustained.
This is both good and bad depending on concerns about volume overload.

I would say that for clinical use 6% albumin and most starches are similar as 
to volume expansion.

I believe our clinicians use LR first and only go to albumin when LR is not 
effective and they don't use any fixed rules.

Also, I believe they prefer LR over NS due to hypercholremic acidosis with 
large volume loads.  I would say that plasmalyte is best crystalloid, but I 
don't see that it is used here much.

At our institution, in ICU and OR it is almost always albumin as the colloids 
and ratios of 1/2 or 1/3 are typically used.  There is strong evidence about 
the dangers and limitations of starches due to renal complications.


George,

George Kramer, PhD
Resuscitation Research Lab
Dept. of Anesthesiology
UTMB, Galveston
409-939-3040






On 2/10/14 5:50 PM, "Daniel Gerard" <[email protected]> wrote:

>Im interested in adding LR as an option for fluid resuscitation, both 
>for the saline availability issue and the problem with hyperchloremic 
>acidosis from NS. Is there any issue with altering serum lactate levels 
>when using large amounts of LR for fluid?
>
>Daniel Gerard RPh
>Critical Care Pharmacist
>McLaren Northern Michigan
>Petoskey, MI 49770
>231-487-4770
>[email protected]
>
>
>
>
>
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------------------------------

Message: 2
Date: Thu, 13 Feb 2014 17:21:11 -0800
From: Joseph Clement <[email protected]>
To: [email protected]
Subject: [Sepsis Groups] Severe Sepsis and Meningitis
Message-ID:
        <of3f2b801b.1321f6ad-on88257c7f.0007364a-88257c7f.00077...@sfgov.org>
Content-Type: text/plain; charset="us-ascii"

Hello

For a patient with sepsis due to meningitis, and who has mild-moderate altered 
mental status as their only organ dysfunction (lactate, BP, Creatine, etc all 
normal), would you consider this to be "severe sepsis", or would you require 
end organ involvement distant from the infection source?

Thanks very much,

Joe
Joseph Clement RN, MS, CCNS
Clinical Nurse Specialist

San Francisco General Hospital
phone: (415) 206-6174
pager: (415) 327-0220
[email protected]
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