Good Luck & Safe travels to you and your team in Haiti.

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Cliff Peebles, 
RN<outbind://23-000000004315E22FCF058346A5246C72F39E671307000CBF5C420BD8AD4AAEDED774BD4A240F000003C2DFC000000CBF5C420BD8AD4AAEDED774BD4A240F000007DE01060000/[email protected]>
Northwestern Medical Center<http://www.northwesternmedicalcenter.org/>
Intensive Care Unit
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From: [email protected] 
[mailto:[email protected]] On Behalf Of 
[email protected]
Sent: Tuesday, March 11, 2014 6:13 AM
To: Ron Elkin
Cc: [email protected]
Subject: [Sepsis Groups] Sepsis Care in third world countries

Good morning all,
I'll be traveling to Haiti in May and I was wondering if anyone out there has 
examples/protocols for care of sepsis patients in those regions where access to 
resources is sparse.  I know that's been an aim of SSC moving forward.  
Obviously, the technology in these areas would likely not permit measurement of 
CVPs/ScVO2, etc, but front-loading of fluids and early antibiotics may be 
feasible with some education of local practitioners.  Any ideas would be much 
appreciated.

Thanks,
Rich Levrault, DO
________________________________
From: "Ron Elkin" <[email protected]<mailto:[email protected]>>
To: "Karin Molander" <[email protected]<mailto:[email protected]>>
Cc: 
[email protected]<mailto:[email protected]>
Sent: Sunday, March 9, 2014 2:12:01 PM
Subject: Re: [Sepsis Groups] Lactates of 2 or greater being discharged or 
admitted to the floor
I believe the SSC data base documents a 23% mortality rate for severe sepsis 
with normal lactate, normal BP at presentation.

There are a number of observational studies in similarly ill severe sepsis 
patients, including that of SSC, documenting a mortality penalty associated 
with triage to the floor before transfer to ICU as compared to triage directly 
to ICU. I'm aware of no studies showing equivalent or better outcomes for 
severe sepsis on telemetry on the floors as compared to ICU, even for the 
not-so-ill patients. I'm aware of no studies randomizing patient assignments to 
ICU, step-down, telemetry, floors and home, and certainly no publications 
advocating home.

In contrast, the mortality rate at Intermountain Health was 8.7% - 9.7% for 
combined septic shock and severe sepsis (lactates 2.0-3.9), with triage to ICU, 
 Miller RR et al. AJRCCM July 2013.

I'm not sure triage to telemetry adds much outcome benefit to to placement on 
the floors. The outcome benefits of ICU and step-down are perhaps more likely 
related to greater frequency of vital signs monitoring (Q1-2H vs Q4H on floors 
and many telemetry units) as well as triage to areas where RNs and MDs are much 
more familiar with recognition and management of severe sepsis.

Based on the above, it seems prudent to triage all patients with severe sepsis 
to ICU or stepdown whenever permitted by bed availability. While lactate 
elevation and/or hypotension are important signs of mortality risk, their 
absence hardly portends a benign outcome.

Ron Elkin, MD
California Pacific Medical Center
San Francisco



On Thu, Mar 6, 2014 at 8:38 AM, Karin Molander 
<[email protected]<mailto:[email protected]>> wrote:
Does anyone have data/article references regarding lactates of 2 being sent 
home or admitted to a floor bed rather than Telemetry bed?

--
Karin H. Molander MD
Mills-Peninsula Hospital
Sutter

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