I am getting different interpretations from different people which is my 
concern. 
They way the guidelines are written it is being interpreted as: (I am 
discussing severe sepsis only not septic shock)

Pt has 2 SIRS & suspected infection, begin 3 hour resuscitation. Screen with 
labs, lactic acid.
IF the lactate is less than 4 the pt gets admitted to the floor NOT the ICU 
irrelevant if they have one or more acute organ dysfunction, no central line 
etc.

This is different than prior guidelines where severe sepsis required EGDT in 
the ICU and was defined as hypo perfusion as indicated by one or more acute 
organ dysfunction OR lactate greater than 4. 

It now seems as if everything is riding on the lactate as the only indicator of 
hypoprofusion.  This seems like a bad idea, you can have hypoprofusion as 
indicated by acute organ dysfunction and a normal lactate.  

Should we be relying on a single indicator of severe sepsis? 

Christine

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