All -


I submitted this question through QualityNet, but was interested in your
thoughts...



The sepsis protocol at our hospital includes the administration of 30
cc/kg crystalloid for hypotension or lactate >=4. If the patient remains
hypotensive after the initial bolus, we have the option of administering
an additional 30 cc/kg. Often this second bolus works to achieve a
sustained MAP >=65.

According to the specifications manual for SEP-1, we *must* start a
vasopressor by the 6th hour if the patient remains hypotensive in the
hour after the initial bolus is complete, correct? The Surviving Sepsis
Campaign's recommendations include "a minimum of 30 mL/kg of
crystalloids" and that "greater amounts of fluid may be needed in some
patients." They go on to say that "fluid administration is continued as
long as there is hemodynamic improvement". My physicians will always go
to more fluids first (if the patient remains fluid responsive) before
starting vasopressors. Can you provide additional
information/clarification so I can educate my clinicians?





Robin Myran, MSN, RN, PCCN

Sepsis Coordinator

Hoag Memorial Hospital Presbyterian

One Hoag Drive

Newport Beach, CA 92658

Office: (949) 764-4588

Fax: (949) 764-5387

Cell: (949) 300-9137

[email protected] <mailto:[email protected]>




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