To all interested List Members.
                        Recently, we gained some interesting data as an
adjunct to some investigations being conducted relative to the use of
MSM/CS eye-drops for several
chronic eye conditions (allergy-induced mucous formation, minor
infections, pathogen-based irritations, etc.) among 50 yr. and older,
human volunteers.
            While MSM-based opthalmic solutions work superbly as
penetrants/transporters
for topically treating the eyes,  there is a side-effect that is worth
commenting upon.
The very characteristics making MSM so effective in these applications,
do---in some cases---cause minor  secondary complications.  Primarily,
these revolve around the dilution/entraining effect MSM has upon
constituents of the eye-lubrication fluid (tears).  MSM seems to carry
most of the sodium chloride fraction with it.....as it penetrates the
lining tissues.  There exists a RESIDUAL effect from MSM, that
encourages a continued leaching process within the replacement
tear-fluid----a condition that lasts for some minutes after the
administation of the MSM-BASED SOLUTIONS.  While there is little---or
no--immediately detectable  discomfort to the user.......the net effect
is to greatly REDUCE the true lubricational effect of the fluids that
are in direct contact with the exterior of the eye-ball, the lining of
the eye-socket, and the eye-lids.  Evidence of this is, usually,  first
felt by the "volunteer" no earlier than 30+ minutes----or maybe not at
all, if he/she is going directly to bed in the evening.  The first
effect is felt as a slight "dry feeling" along the inner edge of the
eye-lid.  If extensive irrigation has been employed (and no
counter-measures employed), excess mucous accumulation is quite common
during the night-time sleep interval.  This being the result of simple
"mechanical irritation" of the lining surfaces.
                There is a very simple protocol which will mitigate
against these, possible, physical irritations/discomforts.  We irrigate,
liberally, with a sterile normal saline solution or Visine, Murine, etc.
type of commercial products..........within approximately two minutes
AFTER the use of the MSM-based liquid protocols.  This simple addition
will restore full lubrication immediately.  If dry eye-lids are a
complicating factor, the topical application (at bed-time)of
non-prescription materials such as Mercuric-oxide ointment  work quite
well----on all primates.
                    One note of explanation.  The MSM-based solutions do
not cause biological or organic systems problems-----quite the
contrary.  The worst result of this post would be to cause some
"experimenter" to deny themselves the value of MSM-based
eye-drops............when they are indicated by immediate physiological
circumstances.   This post is designed to aid in alleviating possible
physical discomfort......certainly not to discourage the use of such a
BENEFICIAL substance as is MSM.
                                            Sincerely.  Brooks Bradley


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