http://www.reuters.com/article/newsOne/idUSTRE4AR48G20081128

LONDON (Reuters) - Mice fed junk food for nine months showed signs of
developing the abnormal brain tangles strongly associated with
Alzheimer's disease, a Swedish researcher said on Friday.

The findings, which come from a series of published papers by a
researcher at Sweden's Karolinska Institutet, show how a diet rich in
fat, sugar and cholesterol could increase the risk of the most common
type of dementia.

"On examining the brains of these mice, we found a chemical change not
unlike that found in the Alzheimer brain," Susanne Akterin, a researcher
at the Karolinska Institutet's Alzheimer's Disease Research Center, who
led the study, said in a statement.

"We now suspect that a high intake of fat and cholesterol in combination
with genetic factors ... can adversely affect several brain substances,
which can be a contributory factor in the development of Alzheimer's."


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