"How can one test for correct particle size. And why doesn't anyone seemed concerned about consuming CS with large particle size? Seems to me that large particles could cause all types of issues with CS. Such as blockage and build up in small capillaries. Which could lead to the Argyria the so called blue man look."
John, Some interesting questions and I have formed some opinions relative to them. Regarding particle size, I have stated before that it is my belief that large silver particles simply do not get passed through the mucous membranes or intestinal walls and into the bloodstream. While no one has taken issue with that belief, no one has expressed agreement either. A quick look at the intestinal wall permeability from http://www.buzzle.com/articles/leaky-gut-syndrome.html; "Physiology In healthy conditions, GI tract absorbs and transmits molecules that are by-products of digestion process. These molecules can be of amino acids, sugar, vitamins, fatty acids, or minerals which are required by the body for proper functioning of life process. GI tract have got a barrier in form of its intestinal lining. The transmission process across this lining is carried out by means of two ways depending on the size of these molecules. Small molecules (size up to 5000 Daltons) are transmitted across the intestinal lining with help of carrier proteins, a specific type of proteins present in intestine. This carrier protein gets bound with the small molecules of minerals, vitamins, and transmits them across the epithelium by active mechanism of transmission. Larger molecules (size more than 5000 Daltons up to 9200daltons) are transferred by means of passive mechanism. This passive mechanism uses the intercellular path ways or spaces commonly known as Desmosomes. The process is called as 'endocytosis'. Desmosomes are tight junction spaces present in between epithelium cells which don't allow the larger molecules of unwanted material to cross the lining." (When you have time to kill, Google Desmosomes or endocytosis for some interesting reading.) So, 1) The permeability of the intestines allows the passing of molecules up to 9200 Daltons, typically. 2) While Daltons is a measure of molecular weight, 9200 Daltons roughly equates to 13 angstroms or 1.3 nm. 3) As a sanity test, I looked at the size of a molecule of NaEDTA. NaEDTA is sometimes used to test intestinal permeability. Being a relatively large molecule (approximately 11 angstroms) it has roughly a 5% (to maybe 18%) absorption rate. One can measure the levels of NaEDTA in the blood stream and compare it against the expected amount that should have been absorbed over a specific period of time and determine if the permeability of the intestines is too high or too low. The 11 angstrom molecular diameter of NaEDTA correlates well with the 13 angstrom maximum permeability estimate. Based on this, I believe that few silver particles larger than 1.3 nm ever pass into the bloodstream. The larger silver particles just pass on through the digestive system. There are a few sub-nano colloidal silvers available and I believe that this gives them a much larger advantage over large particle colloidal silvers than is expressed by the traditional particle surface area analysis. It also indicates a greater advantage for EIS. Especially when one uses Marshal Dudley's H2O2 protocol and Brooks Bradley's Gatorade protocol with EIS. I do not think you can overstate the value of those two protocols. I would recommend the H2O2 protocol be used with commercial colloidal silvers as well. I have some comments to make on Argyria but I will put that in a separate post. Regards, Steve N -----Original Message----- From: [email protected] [mailto:[email protected]] Sent: Tuesday, February 10, 2009 10:03 AM To: [email protected] Subject: CS>Particle size makes all the difference I have to truly believe that to large of particle size is what cause's the most problems in making CS. As in undesirable materials binding with the CS to make proteins.Purity of substance is the issue! Also know as quality control.I believe consuming large amounts of 10pmm with the smallest particle size would be the only way to consume CS in addressing serious health issues.What determines particle size? How can one test for correct particle size.And why doesn't anyone seemed concerned about consuming CS with large particle size? Seems to me that large particles could cause all types of issues with CS.Such as blockage and build up in small capillaries.Which could lead to the Argyria the so called blue man look. -- The Silver List is a moderated forum for discussing Colloidal Silver. Instructions for unsubscribing are posted at: http://silverlist.org To post, address your message to: [email protected] Address Off-Topic messages to: [email protected] The Silver List and Off Topic List archives are currently down... List maintainer: Mike Devour <[email protected]>
