During a recently-past exploratory
investigation on the effectiveness of life-extension via restricted
caloric intake, we came across some work which greatly excited our
interest.
Our investigations had been centered upon Sir2 (a member of the
sirtuin family of enzymes), which is a known aid in protecting cells
and delaying cell death. As early as 2004 several researchers had ,
successfully,
established the beneficial effects of "overexpressing"
Sir2........upon subjects who were following a restricted caloric
diet. In the original experiments with flies.....life extensions of
57% were achieved. Conversely,
the controls displayed no life extensions. During our
investigations, we happened upon some work being done on utilizing
Resveratrol as a complementary stimulant to supporting the Sir2
actions for life extension.
We were, immediately struck, by the stand-alone effectiveness
displayed by Resveratrol.....in aiding in the prevention of a number
of systemic insults---including hearing loss. However, it was the
suppression of angiogenesis
in cancer evaluations by other research organizations----which
commanded our closest attention.
To shorten this diatribe, I simply
state that our initial investigations do tend to confirm the
synergistic effects of Resveratrol with supplementary sources of
Sir2......to be very substantial. I include a non-technical
information flyer by one of many suppliers of Resveratrol ....to
provide those not conversant with this area of investigation.....at
all. Please acknowledge I am not endorsing their products, I have no
knowledge..at all...of the
usefulness/applicability of their products. One can, simply, ignore
or minimize the commercial hype relating to the peculiar superiority
of their brand of nostrums.
I would encourage interested list
members to conduct a web search on Sir2 and Resveratrol......there is
much useful information available on the Internet.
I hope these comments are of value to some list members.
Sincerely, Brooks Bradley.
http://www.revgenetics.com/resveratrol/?gclid=CK2zu9eniaACFcth2godUlYOkg
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