Hello -

Has anyone heard of silver intraveneously?

Does anyone know any doctors that do that?

Does anyone know a good commercial brand of colloidal ilver that is not
expensive?

Thanks.  I still have the ear infection, which I think is mastoiditis.  The
pathogens have been identified as Klebsiells oxytoca, and citrobacter
freundii complex.--- both anamolous for the ear (mid-ear.)


On Thu, Apr 7, 2016 at 1:20 PM, Bill Kingsbury <[email protected]> wrote:

>
> FDA National Center for Toxicological Research
> NCTR Publications > NCTR Research Highlights
>
> Current Highlight from April 1, 2016
>
>
> http://www.fda.gov/AboutFDA/CentersOffices/OC/OfficeofScientificandMedicalPrograms/NCTR/WhatWeDo/NCTRPublications/ucm076767.htm
>
> Size- and Dose-Dependent Antiviral Effects of Silver Nanoparticles
>
> NCTR scientists have demonstrated both size- and dose-dependent antiviral
> effects of silver nanoparticles (AgNPs) in in vitro assays using feline
> calicivirus (FCV) as a surrogate for human norovirus.  Treatment of
> cultures with 10 nanometer (nm)-sized AgNPs (at doses of 50 and 100
> micrograms per milliliter [µg/mL]) completely inactivated FCV within 2-4
> hours of exposure, resulting in a decrease in the viral titer, an absence
> of cytopathic effects in Crandell-Rees Feline Kidney cells, and a reduction
> in viral capsid protein levels; whereas no effect was observed with 75 and
> 110 nm-sized AgNPs.  The use of AgNPs as antibacterial agents has increased
> in consumer-use products; however, its use as an antiviral agent is still
> an area of active research.  This study is now available online at
> Foodborne Pathogens and Disease:
>
> http://dx.doi.org/10.1089/fpd.2015.2054
>
> For additional information, please contact Sangeeta Khare, Ph.D., Division
> of Microbiology, FDA/NCTR.
>
> >>>
>
> Foodborne Pathogens and Disease - March 2016, ahead of print.
>
> Dose and Size-Dependent Antiviral Effects of Silver Nanoparticles on
> Feline Calicivirus, a Human Norovirus Surrogate
>
> Aschalew Z. Bekele, Kuppan Gokulan, Katherine M. Williams, and Sangeeta
> Khare
>
> ABSTRACT
>
> Objectives: Silver nanoparticles (AgNPs) as antibacterial agents are
> incorporated in many consumer products, while the use as antiviral agents
> is an ongoing area of research. We evaluated the antiviral properties of
> AgNPs of variable sizes (10, 75, and 110 nm) and doses (25, 50, and 100
> µg/mL) at different contact time points against feline calicivirus (FCV), a
> surrogate for norovirus.
>
> Materials and Methods: Antiviral effects of the AgNPs were determined by
> comparing the infectivity of FCV, the appearance of cytopathic effects
> (CPEs), and the integrity of the viral capsid protein in viral suspension
> treated with AgNPs with the untreated controls.
>
> Results: The 10 nm AgNPs at 50 and 100 µg/mL concentrations inactivated
> the FCV beyond the limit of detection, resulting in a decrease of up to 6.5
> log10 viral titer, prevented development of CPEs, and reduction in the
> western blot band signal of the viral capsid protein. No significant
> antiviral effect was observed for the 75 and 110 nm AgNPs.
>
> Conclusions and Applications: These results demonstrate that the antiviral
> effects of AgNPs are both size and dose dependent, thus potential
> applications of AgNPs as antiviral agents to prevent contamination of
> foodborne viruses need to consider size and dose effects.
>
> Copyright©2012 Mary Ann Liebert, Inc. publishers.  All rights reserved,
> USA and worldwide.
>
> http://dx.doi.org/10.1089/fpd.2015.2054
>
> >>>
>
> http://sci-hub.io/
>
> Download the PDF:
>
> "Dose and Size-Dependent Antiviral Effects of Silver Nanoparticles on
> Feline Calicivirus"
>
> http://moscow.sci-hub.io/89110c87b9fd1021ebae66d5b3d4f000/bekele2016.pdf
>
> ( Link may expire - if so, reenter the search. )
>
>
> Bill
>
>
> ..
>
>
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