add indigo naturalis to the list of herbs helpful treating flu and
inflammatory disease.
https://cmjournal.biomedcentral.com/articles/10.1186/s13020-020-00406-x
Indirubin could reduce activation of the chemokine regulated on, the
expression of normal T cell and the secretion of influenza virus . And
this inhibitory effect was also observed as well as influenza virus B.
In/vivo/test, Indirubin can reduce the sensitivity of stress-induced
mice to influenza virus (H1N1), thereby reducing lung injury and
improving survival rate.
Indigo and indirubin have strong killing activity against Japanese
encephalitis virus, which may be related to block virus attachment.
Especially indirubin has a strong protective effect on lethal Japanese
encephalitis virus model [45
<https://cmjournal.biomedcentral.com/articles/10.1186/s13020-020-00406-x#ref-CR45>].
In addition, indigo can inhibit the 3C-like protease (3CL^pro ) of
SARS-coronavirus in dose dependence, which can induce the hydrolysis of
replication enzyme polypeptides 1a and 1ab into functional proteins
