Russ, A compound dissolved in water may exist in two states, depending on the pH of the solution. The first state is the uncharged compound itself and the second is when the compound disassociates into a positive part and negative part, that is , ionised.
Compounds of this type are described as having a KpH of some number, which is a measure of the pH at which the concentration of the ionised compound equals the concentration of the uncharged compound. At some particular pH (which depends upon the structure of the molecule) all the compound in solution will be ionised and at another none will be ionised (simplified for easier understanding). The absorption of ionised compounds is low compared to polar molecules, unless they are attached to amino acids, or are lipid (fat) soluble. Cheers Ivan. ----- Original Message ----- From: "russ e rosser" <[email protected]> To: <[email protected]> Sent: Tuesday, 12 December 2000 15:12 Subject: Re: CS Bio Availability, Was: Re: CS>Unidentified subject! > "Ivan Anderson" <[email protected]> writes: > > The amount of drug absorbed depends on the following > > factors[13,14,73-78]: > > > > ...The degree of the drug's ionization and the pH of the absorption > site > > Ivan, > > Please explain the relation between + of - ionization and pH. This has > escaped by comprehension for some time now... Tx. > > --Russ > > > -- > The silver-list is a moderated forum for discussion of colloidal silver. > > To join or quit silver-list or silver-digest send an e-mail message to: > [email protected] -or- [email protected] > with the word subscribe or unsubscribe in the SUBJECT line. > > To post, address your message to: [email protected] > Silver-list archive: http://escribe.com/health/thesilverlist/index.html > List maintainer: Mike Devour <[email protected]> > --- Outgoing mail is certified Virus Free. Checked by AVG anti-virus system (http://www.grisoft.com). Version: 6.0.219 / Virus Database: 103 - Release Date: 05/12/2000
