Hi James,

These studies have probably already been done as part of investigations into
other questions. It would be a matter of reviewing those papers. Dr Flick's
bibliography would probably be a good place to start.

Good Luck ;-)

Ivan.

PS. If have read claims that silver citrate will release silver ions slowly
in external applications, and will perhaps will do so internally also.

> -----Original Message-----
> From: James Osbourne, Holmes [mailto:[email protected]]
> Sent: Wednesday, 23 May 2001 11:57
> To: [email protected]
> Subject: RE: CS>Saliva Experiment Results
>
>
> Correction:
>
> Is there a method for selectively binding silver ions compounds
> or complexes
> in serum?
> If, so quantitative methods may be employed to measure the amount of bound
> silver v. the free silver.  Identifying the complexes/molecules containing
> silver---based on the reaction products---may give some insight into the
> transport mechanism, and some idea of what charge relationships
> may free the
> Ag ions at the point of interface with pathogens.
>
>
> James-Osbourne: Holmes
>
> -----Original Message-----
> From: James Osbourne, Holmes [mailto:[email protected]]
> Sent: Tuesday, May 22, 2001 12:54 PM
> To: [email protected]
> Subject: RE: CS>Saliva Experiment Results
>
> Is there a method for selectively binding silver ions or
> complexes in serum?
> If, so quantitative methods may be employed to measure the amount of bound
> silver v. the free silver.  Identifying the complexes/molecules containing
> silver---based on the reaction products---may give some insight into the
> transport mechanism, and some idea of what charge relationships
> may free the
> Ag ions at the point of interface with pathogens.
>
> James-Osbourne: Holmes
>
> -----Original Message-----
> From: A.V.R.A [mailto:[email protected]]
> Sent: Tuesday, May 22, 2001 10:33 AM
> To: Silver-List
> Subject: Re: CS>Saliva Experiment Results
>
> Ivan,
>
> ( You probably have a much larger audience than you realize )
>
> You bring up a great point about the amount of colloidal silver ingested
> through protein binding.  However, I think even these small
> amounts ingested
> via this method can prove significant over long term use, and therefore
> believe that the idea is still worthy of consideration.  I don't believe,
> when speaking "in vitro", that large amounts of colloidal silver
> are needed
> IF the colloidal silver is reaching the desired location in the
> body.  If an
> "infection" in the body is being managed by the immune system but not
> eliminated ( as is the case with many infections, else one would not live
> very long ) then a one percent increase in the elimination of the
> infection
> can very well "turn the tide".  Of course, this IS simplified.
>
> I believe there is a VERY significant difference in how colloidal silver
> works in a test tube, when placed ON the body, and when used IN the body.
>
> I am convinced that SOMETHING must be occuring that we haven't
> isolated yet.
> Even if colloidal silver is adsorbed through the upper intestinal tract,
> Frank et al is correct in questioning how colloidal silver retains its
> effectiveness once hitting the blood stream ( of course their is
> the ammonia
> hypothesis, which I really need to explore further to achieve a full
> understanding ).
>
> I know that if the stomach is not producing stomach acids, that the
> effectiveness of colloidal silver ingested is greatly improved ( as in the
> case when someone has not ingested foods for a long period of time ).
> However, this does not alone explain an increase in efficacy.
>
> Where else can colloidal silver "bind" with these protein chains?
>
> I know that on this list, side effect reports are scarce ( it is
> the nature
> of this list ).
>
> However, in the short time my website has been up, I've received a few
> correspondences ( and eventually anticipate more ) that are quite
> interesting.  Of course, I strongly encourage people to speak up about any
> interesting effects.
>
> In particular, one individual started using a few SPRAYS per day in the
> mouth, and shortly thereafter discovered that using any brand of
> blond hair
> dye turned her hair orange.  Upon stopping use for about a month, the hair
> dye's effect returned to the expected norm.  This was from less than a
> teaspoon of colloidal silver use per day.  Of course, there are valid
> questions about the type of colloidal silver, ect.
>
> If we start with the assumption that the information reported was
> accurate,
> then it is clear that a very strong metabolic effect was induced
> through the
> colloidal silver use ( obviously, the colloidal silver itself did
> not cause
> this condition ).  I certainly haven't been able to reproduce such an
> effect.
>
> Wouldn't it be relatively easy to create these protein chains
> which preserve
> the ionic silver?
>
>
>
>
>
> ----- Original Message -----
> From: Ivan Anderson <[email protected]>
> To: <[email protected]>
> Sent: Tuesday, May 22, 2001 1:22 AM
> Subject: RE: CS>Saliva Experiment Results
>
>
> > Stuart, Frank, Bob,
> >
> > I do not think that the idea that there can be a protective
> effect by the
> > binding of proteins to silver ions is valid. There may be some
> sublingual
> > absorption of silver, given that the silver binds to transport proteins,
> but
> > the amount of saliva is small, and the concentration of proteins whilst
> > large in variants is small in concentration...less than 1% of plasma.
> > Therefore most of the silver will progress to the stomach, and we have
> been
> > here before!
> >
> > It is obvious to my mind, that silver ions are absorbed in the upper
> > intestine (by methods including those mentioned by Stuart) and
> follow the
> > same route as other ions such as copper and calcium. When they cross the
> > basal membrane of the intestinal lumen and emerge in the plasma
> most will
> be
> > attached to proteins such as albumin and metallothionine, and are
> available
> > to interact with molecules which are attractive enough to relieve the
> > proteins of its cargo (so to speak). This might include groups found on
> the
> > cells walls of pathogens. Otherwise the are transported throughout the
> body
> > and ultimately excreted.
> >
> > The fact that silver ions complex with chloride is neither here
> nor there
> in
> > my opinion, and while finding the exact method of absorption is a
> > stimulating pursuit ;-) the outcome will not be changed by it.
> >
> > By the way, Stuart, I looked at the information given at the link you
> > supplied (http://www.health2us.com/transport.htm), and found a paragraph
> > written by me on another list is quoted word for word (twice! with no
> > reference), and I thought no one was listening.
> >
> > Regards
> > Ivan.
> >
> > > -----Original Message-----
> > > From: Frank Key [mailto:[email protected]]
> > > Sent: Tuesday, 22 May 2001 10:52
> > > To: Silver List
> > > Subject: CS>Saliva Experiment Results
> > >
> > >
> > > While not a rigorous scientific experiment, this simple experiment was
> > > devised to test the theory that saliva contains proteins that will
> > > prevent the silver ions in colloidal silver from combining with
> > > chloride.
> > >
> > > The experiment was conducted on 21 May 2001 at the Colloidal Science
> > > Laboratory and the results have been photographically recorded and
> > > presented with the results.
> > >
> > > The results can be viewed at:
> > >
> > >
http://www.silver-colloids.com/Reports/experiment/SalivaExperiment.html
> >
> >
> > frank key
> >
> >
> > --
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>