Dear Ivan, Brief thoughts provided to your questions: 1.Silver oxide intermediate requires dissolved oxygen. 2. The oligodynamic action of silver release may occur in plain water or biological fluids. 3. More free silver ions are available in plain water because of less reactive molecular species to react with. 4. Reference on oligodynamic can be found in the literature between 1890 and 1910. 5. The reaction of the metalic silver surface and the bacterial cell wall is most likely a reduction oxidation process to a major extent and a non covalent reaction to a minor extent. The silver oxide imtermediate is probably not a factor with respect to the solubility factors of silver oxide. 6.The debate between ionic versus elemental silver rests with accurate data via atomic absroption spectroscopy to know the actual percentages of ionic versus elemental and electron microscopy. Lots of speculation but very little hard data. Please understand the silver can have an effect in an ionic form and a metalic form. The better of the two forms is not possible for me to know based upon the data. Bart Flick M.D.
Ivan Anderson wrote: > > -----Original Message----- > > From: Bart Flick [mailto:[email protected]] > > Sent: Sunday, 26 August 2001 01:37 > > To: *Silver-List* > > Subject: CS>Silverlon > > Thank you Dr Flick. > > I stand corrected in my reference stem cells, I had assumed there would be a > stem cell like intermediary between the fibroblast and final cell > morphology. > > And might I say, I think you have a marvellous product in Silverlon, and > wish you every success with it, not least for the relief it will bring those > unfortunate enough to require its use. > > Sir, I grave your indulgence for a moment. I am most interested in the > development of silver oxide, that you mention, I presume at the silver/ > liquid interface. Does this involve the presence of dissolved oxygen gas, > and will this occur in plain water or are biological fluids required? I > believe that the discovery of this phenomenon gave rise to the term > oligodynamic, and that some investigation has been done on this subject in > the past, but I have been unable to find any reference to this so far. > > You also mention the direct contact of pathogen cell walls with the silver > metal, does this result in the bonding of a silver ion to cell wall sites, > or the catalytic oxidation by adsorbed oxygen, or perhaps both? > > And at the risk of asking you too much...we have been debating the merits of > ingesting colloidal silver with a high ionic content vs a CS with a high > elemental silver content. If you have some knowledge of the subject, could > you comment upon the absorption, and efficacy of the two, and whether we can > expect to find multi-atom clusters which have lost electrons, and are thus > positively charged, in a colloidal silver solution. > > Many thanks, > Ivan. > > > Subject: Silverlon > > Date: Sat, 25 Aug 2001 09:32:22 -0400 > > From: Bart Flick <[email protected]> > > Organization: argentum > > To:*Silver-List* <[email protected]> > > CC: Tom Miller <[email protected]>, SILVER <[email protected]> > > A.B.Flick MD writes: > > My partner and CEO of Argentum Medical, Mr. Gregg Silver, asked that I > > comment on recent E-mails. > > With respect to Mr Andersons comments 24 August 2001: > > 1. The antimicrobial activityof silver rests upon the interaction of > > silver with the bacteria's cellular membrane. This interaction can > > occur through the presence of a silver ion in solution or the release of > > > > silver in an ionic moiety directly from the surface of metalic silver > > when a bacterial cell membrane comes in direct contact with the metalic > > surface. With respect to Silverlon the antimicrobial activity is a > > result of free silver ions (released through a silver oixide > > intermediate) in solution interacting with the bacterial cell membrane > > or direct contact of the bacterial cell membrane on the metalic > > surface. The metalic surface area of Silverlon is at least 1000 fold > > greater that the geometric surface area of the fabric due to the uniform > > > > circumferential plating of metalic silver to the polymer substrate and > > the molecular terrain (shown on tunneling electron microscope). As with > > > > the reference to water filtratio, the name of the game in antimicrobial > > activity is surface area. > > 2. Driving silver ions via an electrical gradient increases the ionic > > silver release between 4 to 8 fold as well as the depth of penetration > > of silver ions into the surrrounding tissue. Bimetalic applications is > > directly dependent upon the surface area of the bimetalic junctions with > > > > metals more noble that silver (i.e. gold platinum etc) but not less > > noble (i.e. copper) > > 3. The patents will give one only a brief overview. > > 4. Silver ions in the proper concentration cause fibroblasts to alter > > their normal cellular morphology. To say that silver ions create stem > > cels is unfounded from my reading of the literature and my work over the > > > > past 25 years. > > With respect to Marshall's comments 24 August 2001: > > 1. The finger tip amputation case was my patient. The tip was amputated > > > > through the lower third of the nailbed with the nail matrix intact. > > 2. With respect to amputated finder tips in children, please refer to > > the Illingsworth paper in the early 1970's. The key to understanding > > this case rests with understanding the basic mechanisms of mainatining a > > > > "blastema". From my experience three key elements are essential: (1) > > proper moisture levels, (2) proper conductivity and (3) proper control > > of wound bioburden. > > With respect to Solar's comments 24 August 2001: > > 1. Agree that all silver containing products are NOT equal. > > 2. With reference to Dr. Becker statements, I do not feel that the > > comments as quoted are not completely correct. While a medical student > > in the 1970's, I had the opportunity to work in Dr. Becker's lab. I > > have the greatest respect for his creativity and intelligence. But I > > stand behind my comments referenced above. > > With kind regards, > > Bart Flick M.D. > > -- > The silver-list is a moderated forum for discussion of colloidal silver. > > To join or quit silver-list or silver-digest send an e-mail message to: > [email protected] -or- [email protected] > with the word subscribe or unsubscribe in the SUBJECT line. > > To post, address your message to: [email protected] > Silver-list archive: http://escribe.com/health/thesilverlist/index.html > List maintainer: Mike Devour <[email protected]>
