It is possible that mice and rats don't have a bbb, or don't have a very good
one?  For the purpose of keeping toxic metals out of the brain, the human would
need this since they live over 50 years, but a rat which dies much sooner, would
likely not accumulate enough metal in the brain during it's lifetime to make it
need such an efficient one.

I would feel much more comfortable with studies done on primates or at least
pigs than mice and rats.

Marshall


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