> looked all thru the  nov, 2003 archives and couldn't locate the research on
> tumors.---Acmeair
> What does "grow in the same way" mean, specifically?---Terry
The quote came from their most current bulletin, and apparently it takes 
awhile for their archive to get it---sorry.
It's a free bulletin, here's the full subject excerpt:
"The American Institute of Physics Bulletin of Physics News
Number 686  May 28, 2004  by Phillip F. Schewe and Ben Stein

TO STOP TUMORS, KNOW HOW THEY GROW. Stimulating the immune system in
a certain way can cause immune-system cells to surround tumors and
stop them from growing, researchers have found (Antonio Brú Espino,
Environmental Sciences Research Center, Spanish Research Council,
antonio....@ccma.csic.es,).  Demonstrated in mice, the finding is a
direct result of applying a new universal model of  tumor growth
developed over the last ten years in a collaboration between
scientists at the Spanish Research Council and medical research
centers in
Spain. The researchers have evidence to show that all tumors grow in
the same way, irrespective of the tissue or species in which they
develop (Brú et al., Biophysical Journal, November 2003). In a
previous paper, these researchers reported that tumor growth, rather
than being exponential as commonly believed, is a much slower
"linear" process similar to the growth of certain crystals and other
natural phenomena (Brú et al., Phys.  Rev. Lett, 2 November 1998).
Tumor cells, they have found, grow through the diffusion or
migration of cancer cells at the tumor's outer edges. Only the cells
close to the edge of the tumor proliferate--those inside the tumor
do not, contrary to previous assumptions. According to the
researchers' observations, cells formed at the edge of the tumor
diffuse at the border of the tumor mass until they settle in curved
depressions where the competition for space is lowest and where they
are best protected from the immune system.  In their new paper, Brú
and co-workers show that the mechanical pressure exerted by
immune-system cells known as "neutrophils" around mouse tumors can
prevent the diffusion of these cells and thus prevent tumor growth.
In 16 mice with a tumor mass in the muscle, the researchers induced
neutrophil production by administering an immune system booster
known as GM-CSF over two months.  In a short time, they observed
that GM-CSF altered the growth dynamics of the cells. The tumors of
two mice regressed completely and 80-90% tumor-cell death was seen
in the rest.  If the growth dynamics of tumors are universal, there
is every  reason to be hopeful the same result could be obtained in
humans. Knowing how tumors grow, by cell diffusion at the surface,
opens up the possibility of developing new and far more efficient
ways of preventing their enlargement and spread. (Bru et al.,
Physical Review Letters, upcoming)"
Main Site: http://www.aip.org/
jr


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